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Increased incidence of unilateral sudden sensorineural hearing loss in patients with hematological malignancies requiring hematopoietic stem cell transplantation

Authors
 Seong Hoon Bae  ;  Yujin Lee  ;  Jinsei Jung 
Citation
 CLINICAL OTOLARYNGOLOGY, Vol.46(6) : 1278-1281, 2021-11 
Journal Title
CLINICAL OTOLARYNGOLOGY
ISSN
 1749-4478 
Issue Date
2021-11
Keywords
hematological neoplasm ; hematopoietic stem cell transplantation ; incidence ; sudden sensorineural hearing loss
Abstract
Haematopoietic stem cell transplantation (HSCT) may dramatically alter the immunity of a recipient. Transient immunodeficiency that occurs before and after HSCT could be associated with the development of sudden sensorineural hearing loss (SSNHL), which is presumed to be often due to viral aetiology. We found an incidence of SSNHL of 29.4 per 10,000 person-years in patients receiving HSCT, 12-fold higher than reported for background population incidence. Development of SSNHL tended to cluster early after diagnosis of haematological malignancies, rather than around date of treatment with HSCT. Increased risk of unilateral SSNHL in patients with haematological malignancy may relate to underlying disease rather than treatment.
Full Text
https://onlinelibrary.wiley.com/doi/10.1111/coa.13829
DOI
10.1111/coa.13829
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Bae, Seong Hoon(배성훈) ORCID logo https://orcid.org/0000-0001-9243-9392
Jung, Jinsei(정진세) ORCID logo https://orcid.org/0000-0003-1906-6969
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187703
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