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Positive association between the ratio of triglycerides to high-density lipoprotein cholesterol and diabetes incidence in Korean adults

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dc.contributor.author김정연-
dc.date.accessioned2021-12-28T17:51:38Z-
dc.date.available2021-12-28T17:51:38Z-
dc.date.issued2021-09-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187303-
dc.description.abstractBackground: Insulin resistance is associated with the incidence of diabetes and cardiovascular diseases such as myocardial infarction. The ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) (TG/HDL-C ratio) is positively correlated with insulin resistance. This study aimed to investigate the relationship between the TG/HDL-C ratio and the incidence of diabetes in Korean adults. Methods: This retrospective study used data from the National Health Insurance Service-National Health Screening Cohort. The TG/HDL-C ratio was divided into three tertiles, the T1, T2, and T3 groups, based on sex. We estimated the hazard ratios (HRs) and 95% confidence intervals (CIs) for diabetes using multivariate Cox proportional hazards regression analyses. Results: A total of 80,693 subjects aged between 40 and 79 years were enrolled. The median follow-up period was 5.9 years. The estimated cumulative incidence of diabetes in the T1, T2, and T3 groups was 5.94%, 8.23%, and 13.50%, respectively, in men and 4.12%, 4.72%, and 6.85%, respectively, in women. Compared to T1, the fully adjusted HRs (95% CIs) of the T2 and T3 groups for new-onset diabetes were 1.17 (1.06-1.30) and 1.47 (1.34-1.62), respectively, in men and 1.20 (1.02-1.42) and 1.52 (1.30-1.78), respectively, in women. Conclusions: Increased TG/HDL-C ratio was significantly associated with a higher risk of new-onset diabetes in both sexes.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfCARDIOVASCULAR DIABETOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePositive association between the ratio of triglycerides to high-density lipoprotein cholesterol and diabetes incidence in Korean adults-
dc.typeArticle-
dc.contributor.collegeCollege of Nursing (간호대학)-
dc.contributor.departmentDept. of Nursing (간호학과)-
dc.contributor.googleauthorJoungyoun Kim-
dc.contributor.googleauthorSang-Jun Shin-
dc.contributor.googleauthorYe-Seul Kim-
dc.contributor.googleauthorHee-Taik Kang-
dc.identifier.doi10.1186/s12933-021-01377-5-
dc.contributor.localIdA06089-
dc.relation.journalcodeJ00460-
dc.identifier.eissn1475-2840-
dc.identifier.pmid34503545-
dc.subject.keywordCardiometabolic risk factors-
dc.subject.keywordCholesterol-
dc.subject.keywordDiabetes mellitus-
dc.subject.keywordInsulin resistance-
dc.subject.keywordLipoproteins, HDL-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordTriglycerides-
dc.contributor.alternativeNameJoungyoun Kim-
dc.contributor.affiliatedAuthor김정연-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage183-
dc.identifier.bibliographicCitationCARDIOVASCULAR DIABETOLOGY, Vol.20(1) : 183, 2021-09-
Appears in Collections:
3. College of Nursing (간호대학) > Dept. of Nursing (간호학과) > 1. Journal Papers

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