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Positive association between the ratio of triglycerides to high-density lipoprotein cholesterol and diabetes incidence in Korean adults
DC Field | Value | Language |
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dc.contributor.author | 김정연 | - |
dc.date.accessioned | 2021-12-28T17:51:38Z | - |
dc.date.available | 2021-12-28T17:51:38Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187303 | - |
dc.description.abstract | Background: Insulin resistance is associated with the incidence of diabetes and cardiovascular diseases such as myocardial infarction. The ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) (TG/HDL-C ratio) is positively correlated with insulin resistance. This study aimed to investigate the relationship between the TG/HDL-C ratio and the incidence of diabetes in Korean adults. Methods: This retrospective study used data from the National Health Insurance Service-National Health Screening Cohort. The TG/HDL-C ratio was divided into three tertiles, the T1, T2, and T3 groups, based on sex. We estimated the hazard ratios (HRs) and 95% confidence intervals (CIs) for diabetes using multivariate Cox proportional hazards regression analyses. Results: A total of 80,693 subjects aged between 40 and 79 years were enrolled. The median follow-up period was 5.9 years. The estimated cumulative incidence of diabetes in the T1, T2, and T3 groups was 5.94%, 8.23%, and 13.50%, respectively, in men and 4.12%, 4.72%, and 6.85%, respectively, in women. Compared to T1, the fully adjusted HRs (95% CIs) of the T2 and T3 groups for new-onset diabetes were 1.17 (1.06-1.30) and 1.47 (1.34-1.62), respectively, in men and 1.20 (1.02-1.42) and 1.52 (1.30-1.78), respectively, in women. Conclusions: Increased TG/HDL-C ratio was significantly associated with a higher risk of new-onset diabetes in both sexes. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | CARDIOVASCULAR DIABETOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Positive association between the ratio of triglycerides to high-density lipoprotein cholesterol and diabetes incidence in Korean adults | - |
dc.type | Article | - |
dc.contributor.college | College of Nursing (간호대학) | - |
dc.contributor.department | Dept. of Nursing (간호학과) | - |
dc.contributor.googleauthor | Joungyoun Kim | - |
dc.contributor.googleauthor | Sang-Jun Shin | - |
dc.contributor.googleauthor | Ye-Seul Kim | - |
dc.contributor.googleauthor | Hee-Taik Kang | - |
dc.identifier.doi | 10.1186/s12933-021-01377-5 | - |
dc.contributor.localId | A06089 | - |
dc.relation.journalcode | J00460 | - |
dc.identifier.eissn | 1475-2840 | - |
dc.identifier.pmid | 34503545 | - |
dc.subject.keyword | Cardiometabolic risk factors | - |
dc.subject.keyword | Cholesterol | - |
dc.subject.keyword | Diabetes mellitus | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Lipoproteins, HDL | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Triglycerides | - |
dc.contributor.alternativeName | Joungyoun Kim | - |
dc.contributor.affiliatedAuthor | 김정연 | - |
dc.citation.volume | 20 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 183 | - |
dc.identifier.bibliographicCitation | CARDIOVASCULAR DIABETOLOGY, Vol.20(1) : 183, 2021-09 | - |
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