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Differences and similarities between the upper and lower airway: focusing on innate immunity

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dc.contributor.author김창훈-
dc.contributor.author윤주헌-
dc.contributor.author이상남-
dc.contributor.author조형주-
dc.contributor.author하종균-
dc.date.accessioned2021-12-28T17:30:29Z-
dc.date.available2021-12-28T17:30:29Z-
dc.date.issued2021-10-
dc.identifier.issn0300-0729-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187133-
dc.description.abstractThe nose is the first respiratory barrier to external pathogens, allergens, pollutants, or cigarette smoke, and vigorous immune responses are triggered when external pathogens come in contact with the nasal epithelium. The mucosal epithelial cells of the nose are essential to the innate immune response against external pathogens and transmit signals that modulate the adaptive immune response. The upper and lower airways share many physiological and immunological features, but there are also numerous differences. It is crucial to understand these differences and their contribution to pathophysiology in order to optimize treatments for inflammatory diseases of the respiratory tract. This review summarizes important differences in the embryological development, histological features, microbiota, immune responses, and cellular subtypes of mucosal epithelial cells of the nose and lungs.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherInternational Rhinologic Society-
dc.relation.isPartOfRHINOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAllergens-
dc.subject.MESHEpithelial Cells-
dc.subject.MESHImmunity, Innate*-
dc.subject.MESHMicrobiota*-
dc.subject.MESHNasal Mucosa-
dc.titleDifferences and similarities between the upper and lower airway: focusing on innate immunity-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Otorhinolaryngology (이비인후과학교실)-
dc.contributor.googleauthorH-J Cho-
dc.contributor.googleauthorJ G Ha-
dc.contributor.googleauthorS N Lee-
dc.contributor.googleauthorC-H Kim-
dc.contributor.googleauthorD-Y Wang-
dc.contributor.googleauthorJ-H Yoon-
dc.identifier.doi10.4193/Rhin21.046-
dc.contributor.localIdA01050-
dc.contributor.localIdA02604-
dc.contributor.localIdA02813-
dc.contributor.localIdA03936-
dc.contributor.localIdA04810-
dc.relation.journalcodeJ03046-
dc.identifier.eissn1996-8604-
dc.identifier.pmid34339483-
dc.identifier.urlhttps://www.rhinologyjournal.com/Abstract.php?id=2916-
dc.contributor.alternativeNameKim, Chang Hoon-
dc.contributor.affiliatedAuthor김창훈-
dc.contributor.affiliatedAuthor윤주헌-
dc.contributor.affiliatedAuthor이상남-
dc.contributor.affiliatedAuthor조형주-
dc.contributor.affiliatedAuthor하종균-
dc.citation.volume59-
dc.citation.number5-
dc.citation.startPage441-
dc.citation.endPage450-
dc.identifier.bibliographicCitationRHINOLOGY, Vol.59(5) : 441-450, 2021-10-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers

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