235 449

Cited 0 times in

Pulsed Electrical Stimulation Enhances Consistency of Directional Migration of Adipose-Derived Stem Cells

DC Field Value Language
dc.contributor.author구민아-
dc.contributor.author박종철-
dc.contributor.author이미희-
dc.date.accessioned2021-12-28T17:25:10Z-
dc.date.available2021-12-28T17:25:10Z-
dc.date.issued2021-10-
dc.identifier.issn2073-4409-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187091-
dc.description.abstractElectrical stimulation is a well-known strategy for regulating cell behavior, both in pathological and physiological processes such as wound healing, tissue regeneration, and embryonic development. Electrotaxis is the directional migration of cells toward the cathode or anode when subjected to electrical stimulation. In this study, we investigated the conditions for enhanced directional migration of electrically stimulated adipose-derived stem cells (ADSCs) during prolonged culture, using a customized agar-salt electrotaxis chamber. Exposure of ADSCs to a 1200 μA electric current for 3 h, followed by cessation of stimulation for 6 h and resumed stimulation for a further 3 h, increased directional cell migration toward the anode without inducing cell death. Moreover, Golgi polarization maintained the direction of polarity parallel to the direction of cell movement. Herein, we demonstrated that a pulsed electric current is sufficient to trigger directional migration of ADSCs in long-term culture while maintaining cell viability.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI-
dc.relation.isPartOfCELLS(Cells)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePulsed Electrical Stimulation Enhances Consistency of Directional Migration of Adipose-Derived Stem Cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentOthers-
dc.contributor.googleauthorMi Hee Lee-
dc.contributor.googleauthorYe Jin Park-
dc.contributor.googleauthorSeung Hee Hong-
dc.contributor.googleauthorMin-Ah Koo-
dc.contributor.googleauthorMinyoung Cho-
dc.contributor.googleauthorJong-Chul Park-
dc.identifier.doi10.3390/cells10112846-
dc.contributor.localIdA00190-
dc.contributor.localIdA01662-
dc.contributor.localIdA02777-
dc.relation.journalcodeJ03774-
dc.identifier.pmid34831069-
dc.subject.keywordGolgi polarization-
dc.subject.keywordadipose-derived stem cells-
dc.subject.keyworddirectional migration-
dc.subject.keywordelectrotaxis-
dc.contributor.alternativeNameKoo, Min-Ah-
dc.contributor.affiliatedAuthor구민아-
dc.contributor.affiliatedAuthor박종철-
dc.contributor.affiliatedAuthor이미희-
dc.citation.volume10-
dc.citation.number11-
dc.citation.startPage2846-
dc.identifier.bibliographicCitationCELLS, Vol.10(11) : 2846, 2021-10-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.