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Evidence based guidelines for the treatment of Helicobacter pylori infection in Korea 2020

Authors
 Hye-Kyung Jung  ;  Seung Joo Kang  ;  Yong Chan Lee  ;  Hyo-Joon Yang  ;  Seon-Young Park  ;  Cheol Min Shin  ;  Sung Eun Kim  ;  Hyun Chul Lim  ;  Jie-Hyun Kim  ;  Su Youn Nam  ;  Woon Geon Shin  ;  Jae Myung Park  ;  Il Ju Choi  ;  Jae Gyu Kim  ;  Miyoung Choi 
Citation
 KOREAN JOURNAL OF INTERNAL MEDICINE, Vol.36(4) : 807-838, 2021-07 
Journal Title
KOREAN JOURNAL OF INTERNAL MEDICINE
ISSN
 1226-3303 
Issue Date
2021-07
MeSH
Amoxicillin / therapeutic use ; Anti-Bacterial Agents / therapeutic use ; Clarithromycin / therapeutic use ; Drug Therapy, Combination ; Helicobacter Infections* / diagnosis ; Helicobacter Infections* / drug therapy ; Helicobacter Infections* / epidemiology ; Helicobacter pylori* ; Humans ; Proton Pump Inhibitors / therapeutic use ; Randomized Controlled Trials as Topic ; Republic of Korea / epidemiology
Keywords
Guidelines ; Helicobacter pylori ; Meta-analysis ; Microbial sensitivity tests ; Treatment
Abstract
Helicobacter pylori infection is one of the most common infectious diseases worldwide. H. pylori is responsible for substantial gastrointestinal morbidity with a high disease burden. Since the revision of the H. pylori Clinical Practice Guidelines in 2013 in Korea, the eradication rate of H. pylori has gradually decreased with the use of a clarithromycin based triple therapy. According to a nationwide randomized controlled study by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance to clarithromycin. The clinical practice guidelines for treatment of H. pylori were updated based on evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after expert consensus on three recommendations regarding the indication for treatment and eight recommendations on the treatment itself. These guidelines were designed to provide clinical evidence for the treatment of H. pylori to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards, and will be revised if more evidence emerges in the future.
Files in This Item:
T202104962.pdf Download
DOI
10.3904/kjim.2020.701
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jie-Hyun(김지현) ORCID logo https://orcid.org/0000-0002-9198-3326
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
Lim, Hyun Chul(임현철)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187043
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