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Inter-institutional Variation in Intensity-modulated Radiotherapy for Breast Cancer in Korea (KROG 19-01)

Authors
 Kyubo Kim  ;  Minsoo Chun  ;  Hyeongmin Jin  ;  Wonguen Jung  ;  Kyung Hwan Shin  ;  Seong Soo Shin  ;  Yeon Joo Kim  ;  Shin-Hyung Park  ;  Jin Hee Kim  ;  Yong Ho Kim  ;  Hyun Soo Shin  ;  Haeyoung Kim  ;  Su Ssan Kim  ;  Jong Hoon Lee  ;  Yong Bae Kim  ;  Sun Young Lee  ;  Jinhyun Choi  ;  DO Hoon Oh  ;  Ki Mun Kang  ;  Jeanny Kwon  ;  Mi Young Kim  ;  Taeryool Koo  ;  Hae Jin Park  ;  Sung Ja Ahn 
Citation
 ANTICANCER RESEARCH, Vol.41(6) : 3145-3152, 2021-06 
Journal Title
ANTICANCER RESEARCH
ISSN
 0250-7005 
Issue Date
2021-06
MeSH
Breast Neoplasms / diagnostic imaging ; Breast Neoplasms / radiotherapy* ; Female ; Humans ; Interinstitutional Relations ; Middle Aged ; Organs at Risk ; Radiotherapy, Intensity-Modulated / methods* ; Republic of Korea
Keywords
Breast cancer ; dose-volume constraint ; intensity-modulated radiation therapy ; target volume ; variation
Abstract
Background/aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers.

Patients and methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation.

Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case.

Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.
Full Text
https://ar.iiarjournals.org/content/41/6/3145.long
DOI
10.21873/anticanres.15100
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yong Bae(김용배) ORCID logo https://orcid.org/0000-0001-7573-6862
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187009
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