Surveillance of COVID-19-Associated Multisystem Inflammatory Syndrome in Children, South Korea

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Authors: Young June Choe ; Eun Hwa Choi ; Jong Woon Choi ; Byung Wook Eun ; Lucy Youngmin Eun ; Yae-Jean Kim ; Yeo Hyang Kim ; Young A Kim ; Yun-Kyung Kim ; Ji Hee Kwak ; Hyuk Min Lee ; Hyunju Lee ; Joon Kee Lee ; June Dong Park ; Eun-Jin Kim ; Young Joon Park ; Jin Gwack ; Sang Won Lee

MeSH: Adolescent ; COVID-19* / blood ; COVID-19* / complications ; COVID-19* / diagnosis ; COVID-19* / epidemiology ; COVID-19* / physiopathology ; COVID-19* / therapy ; Child ; Diagnosis, Differential ; Diarrhea* / diagnosis ; Diarrhea* / virology ; Exanthema / diagnosis ; Exanthema / etiology ; Female ; Hospitalization ; Humans ; Leukocytosis / diagnosis ; Leukocytosis / etiology ; Male ; Mitral Valve Insufficiency / diagnosis ; Mitral Valve Insufficiency / etiology ; Pleural Effusion* / diagnosis ; Pleural Effusion* / etiology ; Republic of Korea / epidemiology ; SARS-CoV-2* / isolation & purification ; SARS-CoV-2* / pathogenicity ; Systemic Inflammatory Response Syndrome* / blood ; Systemic Inflammatory Response Syndrome* / diagnosis ; Systemic Inflammatory Response Syndrome* / physiopathology ; Systemic Inflammatory Response Syndrome* / therapy ; Tomography, X-Ray Computed / methods ; Treatment Outcome ; Ultrasonography / methods ; Ventricular Dysfunction, Left / diagnosis ; Ventricular Dysfunction, Left / etiology

Keywords: COVID-19 ; Coronavirus disease ; MIS-C ; SARS-CoV-2 ; South Korea ; child ; inflammation ; multisystem inflammatory syndrome ; pediatric ; respiratory infections ; severe acute respiratory syndrome coronavirus 2 ; surveillance ; viruses ; zoonoses

Abstract: A concerning development during the coronavirus disease pandemic has been multisystem inflammatory syndrome in children. Reports of this condition in East Asia have been limited. In South Korea, 3 cases were reported to the national surveillance system for multisystem inflammatory syndrome in children. All case-patients were hospitalized and survived with no major disease sequelae.