공중근무자의 흡연과 10년간 혈청지질 수준과의 관계

Abstract

The purpose of this study was to define the relationship of smoking and blood lipid profiles among airscrews from January 1983 to December 1992 and the influence of smoking to blood lipids. Among 251 aircrew members, 149 were non-smokers (mean age 50.2±6.8 years) and 102 were smokers (mean age 47.8±6.7 years). Serum total cholesterol, serum LDL-cholesterol, serum triglycerides increased significantly with age. In smokers, serum HDL cholesterol was lower and serum triglycerides higher compared to non-smokers. Depending on the amount of cigarettes the serum total cholesterol was lower and the serum HDL-cholesterol was higher in those who consumed less number of cigarettes per day. The longer the period of smoking years the lower the HDL-cholesterol and the higher the serum total cholesterol and serum triglyceride levels. In univariate analysis, there were significant differences in serum HDL-cholesterol and serum triglyceride among smokers and non-smokers. There were no differences in the change rates of blood lipids during the 10 year follow up. Serum total cholesterol and serum triglyceride levels were positively correlated with age, weight and BMI. Serum HDL cholesterol were negatively correlated wuth weight and BMI. Serum LDL cholesterol showed positive correlation with age and weight. Though analysis of the effect of smoking to blood lipids by multiple regression after controlling confounding factors revealed that age had significant effect on serum total cholesterol and serum LDL-cholesterol levels, serum HDL-cholesterol was influenced by stocking, and serum LDL-cholesterol was influenced by smoking and BMI.