당뇨병 환자의 이하선 타액내 Pm의 다형현상에 대한 연구

Abstract

The purpose of this study was to evaluate the polymorphism in parotid middle-band protein(Pm) of the patients with diabetes mellitus, Saliva from the parotid glands was collected from 60 healthy Korean who were live in Kwang-ju and from 33 diabetes mellitus patients who had more than 140mg/dl of fasting blood sugar for on week. In the saliva collected from parotid glands. Pm was analyzed to evaluate the distribution of phenotype using acid-urea starch gel electrophores is The follow results were obtained 1. The phenotypes of parotid middle band protein(Pm) observed in parotid saliva of the control group(60 people) were Pm(+) in 38 people (63.3%) and PM(-) in 22 people(36.7%). The gene frequency of Pmt was 0.394, and that of Pm-was 0.606. 2. The phenotypes of parotid middle band protein(Pm) observed in parotid saliva of the diabetes mellitus patient group(33 patients) were Pm(+) in 21 patients(63.6%) and Pm(-) in 12 patients(36.4%). The gene frequency of Pm-was 0.397, and that of Pm- was 0.603. 3. Pm dose not have significant differences between phenotypes on both the control group and the diabetes mellitus patient group.