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Dimethylthiourea prevents MPTP-induced decrease in [3H]dopamine uptake in rat striatal slices
DC Field | Value | Language |
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dc.contributor.author | 김동구 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2021-12-27T16:57:38Z | - |
dc.date.available | 2021-12-27T16:57:38Z | - |
dc.date.issued | 1995-01 | - |
dc.identifier.issn | 0006-8993 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186279 | - |
dc.description.abstract | The trisomy 16 mouse is a genetic model of Down syndrome. Clonal cell lines were developed from trisomic as well as euploid embryonic mouse septal cells by introduction of thermolabile large T antigen mutant of SV 40. The cell lines underwent morphological differentiation at the non-permissive temperature and in respone to a differentiating agent. Immunocytochemical staining indicated that cells of neuronal lineage were immortalized. The addition of β-nerve growth factor (100 ng/ml) increased the survival rate of a trisomy cell line in differentiated state, as measured by Trypan blue exclusion. These cell lines may prove useful in studies of neuronal abnormalities in this mouse model of Down syndrome. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Amsterdam Elsevier/North-Holland Biomedical Press | - |
dc.relation.isPartOf | BRAIN RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Dimethylthiourea prevents MPTP-induced decrease in [3H]dopamine uptake in rat striatal slices | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pharmacology (약리학교실) | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.contributor.googleauthor | Dong Goo Kim | - |
dc.contributor.googleauthor | Hye Ryun Bahng | - |
dc.contributor.googleauthor | Jin-Soo Kim | - |
dc.identifier.doi | 10.1016/0006-8993(94)01359-P | - |
dc.contributor.localId | A00396 | - |
dc.contributor.localId | A04369 | - |
dc.relation.journalcode | J00392 | - |
dc.identifier.eissn | 1872-6240 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/000689939401359P | - |
dc.contributor.alternativeName | Kim, Dong Goo | - |
dc.contributor.affiliatedAuthor | 김동구 | - |
dc.contributor.affiliatedAuthor | 허지회 | - |
dc.citation.volume | 671 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 321 | - |
dc.citation.endPage | 324 | - |
dc.identifier.bibliographicCitation | BRAIN RESEARCH, Vol.671(2) : 321-324, 1995-01 | - |
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