신장 재 이식

Abstract

Patients with retransplanted were considered at higher risk for failure than prirnary kidney recipients. But the results of kidney retransplantation in the cyclosporine era have improved substantially in recent years. And some author reported that there was no significant difference between the primary kidney recipients and regrafted patients. So we report here the results of regraftui patients and the risk factors affecting the graft survival in regrafted patients at Yonsei university hospital. Among the 1232 patients underwent kidney transplantation with CsA based immunosuppression, 26 patients underwent kidney retransplantation from January,1984 through June,1995 at our hospital. All the regrafted recipients were on triple immunosuppression using CsA, prednisone and AZA. The results of our paper were as follows: l) The prevalence of retransplantation was 2.1% (26 cases of 1232 cases) 2) The most common cause of previous graft loss was chronic rejection (64.3%). 3) There were no significant differences between the retransplant recipients and primary transplant recipients in graft survival rate, patient survival rate and incidence of early rejection. 4) The risk factors affecting the incidence of early rejection were previous graft failure caused by acute rejection, presence of early rejection in the previous graft, length of previous graft survival (less than l year) and cadaveric donor for retransplantation or previous transplantation. Retransplantation is the one of the option for the patients who had failed their previous grafts from any reasons in spite of organ shortage.