Preparation and Characterization of Water-Soluble Glass through Melting Process (I) : Dissolution Characteristics, Bactericidal Effects and Cytotoxicity
Authors
조종호 ; 이용근 ; 최세영 ; 신철수 ; 김경남
Citation
JOURNAL OF THE KOREAN CERAMIC SOCIETY, Vol.32(10) : 1093-1102, 1995-10
Water-soluble ; Phosphate glass ; Ag ion ; Cu ion ; Dissolution ; Bactericidal effect ; Cytotoxicity
Abstract
Water-soluble phosphate glasses containing Ag or Cu ion were prepared through melting process. Then the powdered glass samples were dissolved in D.I. water at room temperature with changing the dissolution time. In terms with the glass composition, dissolution characteristics, bactericidal effects and cytotoxicities were investigated. Dissolved amounts increased uniformly with dissolution time, and the dissolution rate was higher for ternary glass than for binary glass and with less metal oxide amount. And the dissolution rate of the glass with Ag ion was higher than that with Cu ion, and the bactericidal effect of the glass with Ag ion was also greater. Solution with more than 25 ppm of Ag was observed to have strong cytotoxicity to L929, and solutions of lower Ag concentration or with Cu seemed to have little cytotoxicity.