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Invasive dental procedures as risk factors for postoperative spinal infection and the effect of antibiotic prophylaxis

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dc.date.accessioned2021-11-19T01:41:42Z-
dc.date.available2021-11-19T01:41:42Z-
dc.date.issued2021-09-
dc.identifier.issn0303-6979-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/185984-
dc.description.abstractAim: To identify invasive dental procedures as a risk factor for postoperative spinal infection (PSI) and evaluate the effectiveness of antibiotic prophylaxis. Materials and methods: We analysed 229,335 patients who underwent spinal surgery with instrumentation from 2010 to 2017, using the nationwide database. The incidence of spinal infection 2 years after surgery was determined. Invasive dental procedures as a risk factor for PSI and the effects of antibiotic prophylaxis during this period were also analysed. Results: A total of 15,346 patients (6.69%) were diagnosed with PSI. It was found that advanced age, male sex, and a high Charlson Comorbidity Index were risk factors for PSI. The risk of PSI did not increase following dental procedures (adjusted hazard ratio [HR] 0.850; 95% confidence interval [CI], 0.793-0.912) and was not affected by antibiotics (adjusted HR 1.097; 95% CI, 0.987-1.218). Patients who received dental treatment as early as 3 months after spinal surgery had the lowest risk of postoperative infection (adjusted HR 0.869; 95% CI, 0.795-0.950). Conclusions: Invasive dental procedure does not increase the risk of PSI, and antibiotic prophylaxis before dental procedure was not effective in preventing spinal infection.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherWiley-Blackwell-
dc.relation.isPartOfJOURNAL OF CLINICAL PERIODONTOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAnti-Bacterial Agents* / therapeutic use-
dc.subject.MESHAntibiotic Prophylaxis*-
dc.subject.MESHDentistry-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHPostoperative Complications-
dc.subject.MESHRisk Factors-
dc.titleInvasive dental procedures as risk factors for postoperative spinal infection and the effect of antibiotic prophylaxis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Orthopedic Surgery (정형외과학교실)-
dc.contributor.googleauthorSahyun Sung-
dc.contributor.googleauthorEun Hwa Kim-
dc.contributor.googleauthorJi-Won Kwon-
dc.contributor.googleauthorJung-Seok Lee-
dc.contributor.googleauthorSoo-Bin Lee-
dc.contributor.googleauthorSeong-Hwan Moon-
dc.contributor.googleauthorHwan-Mo Lee-
dc.contributor.googleauthorInkyung Jung-
dc.contributor.googleauthorByung Ho Lee-
dc.identifier.doi10.1111/jcpe.13514-
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dc.relation.journalcodeJ01337-
dc.identifier.eissn1600-051X-
dc.identifier.pmid34189757-
dc.subject.keywordantibiotic prophylaxis-
dc.subject.keywordinvasive dental procedure-
dc.subject.keywordnationwide database-
dc.subject.keywordpostoperative spinal infection-
dc.subject.keywordspinal surgery-
dc.contributor.alternativeNameKwon, Ji-Won-
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dc.citation.volume48-
dc.citation.number9-
dc.citation.startPage1270-
dc.citation.endPage1280-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL PERIODONTOLOGY, Vol.48(9) : 1270-1280, 2021-09-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers

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