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Impact of the Human Microbiome on Nephrolithiasis

Authors
 Hae Do Jung  ;  Joo Yong Lee 
Citation
 Urogenital Tract Infection, Vol.16(2) : 25-31, 2021-08 
Journal Title
Urogenital Tract Infection
ISSN
 2465-8243 
Issue Date
2021-08
Keywords
Microbiota ; Nephrolithiasis ; Gastrointestinal microbiome
Abstract
Nephrolithiasis has many causes, and its prevalence is increasing worldwide. The interest in the human microbiome is growing because of the advance of new diagnostic techniques, and recent studies have suggested a link between the microbiome and nephrolithiasis. This paper reviewed the role of the microbiome in nephrolithiasis. The absence of Oxalobacter formigenes induces hyperoxaluria, which promotes calcium oxalate stone (CaOx) formation. Escherichia coli promote CaOx supersaturation through hypocitraturia caused by the bacterial production of citrate lyase. Infection stones are associated with urea-splitting organisms, particularly Proteus mirabilis, and the stones themselves contain many species of bacteria
Files in This Item:
T202104535.pdf Download
DOI
10.14777/uti.2021.16.2.25
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Joo Yong(이주용) ORCID logo https://orcid.org/0000-0002-3470-1767
Jung, Hae Do(정해도)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185977
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