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Vulvar Crohn's disease in an adolescent diagnosed after unsuccessful surgical treatment

Authors
 Suhra Kim  ;  Young Bin Won  ;  Seok Kyo Seo  ;  SiHyun Cho  ;  Young Sik Choi  ;  Byung Seok Lee  ;  Bo Hyon Yun 
Citation
 BMC WOMENS HEALTH, Vol.21(1) : 316, 2021-08 
Journal Title
BMC WOMENS HEALTH
Issue Date
2021-08
MeSH
Adolescent ; Azathioprine ; Crohn Disease* / complications ; Crohn Disease* / diagnosis ; Crohn Disease* / drug therapy ; Female ; Humans ; Recurrence ; Vulvar Diseases* / diagnosis ; Vulvar Diseases* / surgery
Keywords
Metastatic Crohn’s disease ; Vulvar Crohn’s disease ; Vulvar abscess ; Vulvar inflammation
Abstract
Background: This case report presents a case of Vulvar Crohn's disease (VCD) in an adolescent, that is an uncommon manifestation of Crohn's disease (CD) without gastrointestinal symptoms. Before treating CD itself with proper medication, vulvar abscess continued to recur without improvement.

Case presentation: We report the case of an 18-year-old woman with VCD. After treatment with azathioprine 50 mg daily and mesalazine 1 g three times daily, vulvar lesions resolved after 6 weeks. We collected electronic medical data on patient characteristics, and evaluated findings of physical examinations, pelvic MRI, and biopsy specimen obtained from gastroduodenoscopy/colonoscopy.

Conclusions: VCD is a rare manifestation of CD that may be misdiagnosed in the absence of gastrointestinal symptoms leading to delayed treatment. If a patient has an unexplained vulvar inflammatory lesion and with repeated failed surgical treatment, gynecologists should consider the possibility of a VCD.
Files in This Item:
T202104080.pdf Download
DOI
10.1186/s12905-021-01449-4
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Seo, Seok Kyo(서석교) ORCID logo https://orcid.org/0000-0003-3404-0484
Won, Young Bin(원영빈) ORCID logo https://orcid.org/0000-0002-7345-7090
Yun, Bo Hyon(윤보현) ORCID logo https://orcid.org/0000-0001-5703-797X
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
Cho, Si Hyun(조시현) ORCID logo https://orcid.org/0000-0003-2718-6645
Choi, Young Sik(최영식) ORCID logo https://orcid.org/0000-0002-1157-4822
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185414
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