Cited 1 times in
Clinical Spectrum of Uveal Metastasis in Korean Patients Based on Primary Tumor Origin
DC Field | Value | Language |
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dc.contributor.author | 강현구 | - |
dc.contributor.author | 고형준 | - |
dc.contributor.author | 김민 | - |
dc.contributor.author | 김성수 | - |
dc.contributor.author | 변석호 | - |
dc.contributor.author | 이성철 | - |
dc.date.accessioned | 2021-10-21T00:10:57Z | - |
dc.date.available | 2021-10-21T00:10:57Z | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 2468-7219 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/185413 | - |
dc.description.abstract | Purpose: To describe the clinical features and prognosis of patients with uveal metastasis in Korea. Design: Retrospective, observational case series. Participants: Patients diagnosed at 2 tertiary high-volume centers between November 2005 and November 2019. Methods: Evaluation of multimodal imaging and electronic medical records. Main outcome measures: The clinical features and outcomes were assessed based on the primary cancer site. Results: A total of 134 uveal metastases (128 choroidal, 3 iris, and 3 ciliary body tumors) were diagnosed in 95 eyes of 80 patients. Mean age at diagnosis was 56 years (median, 55 years; range, 24-86 years), with a minor preponderance of women (61%). Tumors were bilateral in 15 patients (19%) and the primary origin was established in 49 patients (61%) before ocular detection. The primary tumor originated in the lung (48%), breast (24%), gastrointestinal tract (10%), liver (3%), pancreas (3%), kidney (1%), cervix (1%), and nasopharynx (1%), with some remaining unknown (10%). The overall 5-year survival rate was 21%. Kaplan-Meier analysis revealed that the worst survival was found in pancreatic cancers (mean survival, 5.9 months; P = 0.045), and the best survival was found in gastrointestinal tract cancers (mean survival, 44.5 months). Conclusions: The primary tumor origins in Korean patients with uveal metastases differed from those reported in primarily population-based studies of White patients, with a higher prevalence of lung and gastrointestinal tract cancers. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | OPHTHALMOLOGY RETINA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Clinical Spectrum of Uveal Metastasis in Korean Patients Based on Primary Tumor Origin | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Hyun Goo Kang | - |
dc.contributor.googleauthor | Minha Kim | - |
dc.contributor.googleauthor | Suk Ho Byeon | - |
dc.contributor.googleauthor | Sung Soo Kim | - |
dc.contributor.googleauthor | Hyoung Jun Koh | - |
dc.contributor.googleauthor | Sung Chul Lee | - |
dc.contributor.googleauthor | Min Kim | - |
dc.identifier.doi | 10.1016/j.oret.2020.09.007 | - |
dc.contributor.localId | A04873 | - |
dc.contributor.localId | A00152 | - |
dc.contributor.localId | A00455 | - |
dc.contributor.localId | A00571 | - |
dc.contributor.localId | A01849 | - |
dc.contributor.localId | A02873 | - |
dc.relation.journalcode | J04087 | - |
dc.identifier.eissn | 2468-6530 | - |
dc.identifier.pmid | 32942025 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S2468653020303717 | - |
dc.subject.keyword | Choroidal tumor | - |
dc.subject.keyword | Intraocular tumor | - |
dc.subject.keyword | Primary tumor origin | - |
dc.subject.keyword | Survival | - |
dc.subject.keyword | Uveal metastasis | - |
dc.contributor.alternativeName | Kang, Hyun Goo | - |
dc.contributor.affiliatedAuthor | 강현구 | - |
dc.contributor.affiliatedAuthor | 고형준 | - |
dc.contributor.affiliatedAuthor | 김민 | - |
dc.contributor.affiliatedAuthor | 김성수 | - |
dc.contributor.affiliatedAuthor | 변석호 | - |
dc.contributor.affiliatedAuthor | 이성철 | - |
dc.citation.volume | 5 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 543 | - |
dc.citation.endPage | 552 | - |
dc.identifier.bibliographicCitation | OPHTHALMOLOGY RETINA, Vol.5(6) : 543-552, 2021-06 | - |
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