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BMI, weight change, and incidence of disability among Korean adults: A nationwide retrospective cohort study

Authors
 Jae Woo Choi  ;  Tae Hyun Kim  ;  Euna Han 
Citation
 DISABILITY AND HEALTH JOURNAL, Vol.14(4) : 101104, 2021-10 
Journal Title
DISABILITY AND HEALTH JOURNAL
ISSN
 1936-6574 
Issue Date
2021-10
Keywords
BMI ; Disability ; Longitudinal cohort study ; Weight change
Abstract
Background: Little is known about the risk of acquired disability diagnosed by a physician in relation to baseline BMI and weight change, particularly in the Asian population. Objective: This study assessed the association of baseline BMI and weight change with incidence of disability. Methods: This study included 331,900 individuals aged ≥40 years who participated in two health-screening programs since 2002 or 2003 and who were followed up until 2013. This study measured the baseline BMI and weight change for two years and estimated the adjusted hazard ratio (aHR) of the risk of acquired disability diagnosed by a physician using a Cox proportional hazards model. Results: This study identified 1758 incident disability cases during an average follow-up period of 10.7 ± 1.3 years from baseline (9.1 ± 1.4 years from the follow-up health screening). Baseline underweight (BMI<18.5 kg/m2) was associated with an increased risk of acquired disability compared with those with normal BMI (aHR, 1.44; 95% confidence interval [CI], 1.14-1.83). The risk of acquired disability was higher in individuals with weight loss of 5-10% (aHR, 1.21; 95% CI, 1.04-1.40), weight loss of ≥10% (aHR, 1.61; 95% CI, 1.27-2.04), weight gain of 5-10% (aHR, 1.30; 95% CI, 1.12-1.52), or weight gain of ≥10% (aHR, 1.35; 95% CI, 1.09-1.75) compared to those with weight change of <5%. Conclusion: This study demonstrated that baseline underweight and weight changes (both loss and gain) are associated with an increased risk of acquired disability.
Full Text
https://www.sciencedirect.com/science/article/pii/S1936657421000509
DOI
10.1016/j.dhjo.2021.101104
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Kim, Tae Hyun(김태현) ORCID logo https://orcid.org/0000-0003-1053-8958
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185404
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