Cited 11 times in
The association between urinary bisphenol A levels and nonalcoholic fatty liver disease in Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015-2017
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 양은정 | - |
dc.date.accessioned | 2021-10-21T00:08:12Z | - |
dc.date.available | 2021-10-21T00:08:12Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.issn | 1342-078X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/185391 | - |
dc.description.abstract | Background: Nonalcoholic fatty liver disease (NAFLD) is becoming a global health problem. Bisphenol A (BPA), one of most widely used environmental chemicals, is suspected to be a contributor to the development NAFLD. This study was performed to examine the relationship between human BPA levels and risk of NAFLD. Methods: The data (n = 3476 adults: 1474 men and 2002 women) used in this study were obtained from the Korean National Environmental Health Survey III (2015-2017). BPA levels were measured in urine samples. NAFLD was defined using hepatic steatosis index after exclusion of other causes of hepatic diseases. Results: There was a significant linear relationship between the elevated urinary BPA concentrations and risk of NAFLD. In a univariate analysis, odds ratio (OR) of the highest quartile of urinary BPA level was 1.47 [95% confidence interval (CI) 1.11-1.94] compared to the lowest quartile. After adjusted with covariates, the ORs for NAFLD in the third and fourth quartiles were 1.31 [95% CI 1.03-1.67] and 1.32 [95% CI 1.03-1.70], respectively. Conclusions: Urinary BPA levels are positively associated with the risk of NAFLD in adults. Further experimental studies are needed to understand the molecular mechanisms of BPA on NAFLD prevalence. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | The association between urinary bisphenol A levels and nonalcoholic fatty liver disease in Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015-2017 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Plastic and Reconstructive Surgery (성형외과학교실) | - |
dc.contributor.googleauthor | Sang Joon An | - |
dc.contributor.googleauthor | Eun-Jung Yang | - |
dc.contributor.googleauthor | Subin Oh | - |
dc.contributor.googleauthor | Kyong Jin Park | - |
dc.contributor.googleauthor | Taehyen Kim | - |
dc.contributor.googleauthor | Yeon-Pyo Hong | - |
dc.contributor.googleauthor | Yun-Jung Yang | - |
dc.identifier.doi | 10.1186/s12199-021-01010-7 | - |
dc.contributor.localId | A05927 | - |
dc.relation.journalcode | J03338 | - |
dc.identifier.eissn | 1347-4715 | - |
dc.identifier.pmid | 34521354 | - |
dc.subject.keyword | Bisphenol A | - |
dc.subject.keyword | Hepatic steatosis index | - |
dc.subject.keyword | Korean adults | - |
dc.subject.keyword | Korean national environmental health survey | - |
dc.subject.keyword | Nonalcoholic fatty liver disease | - |
dc.contributor.alternativeName | Yang, Eun-Jung | - |
dc.contributor.affiliatedAuthor | 양은정 | - |
dc.citation.volume | 26 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 91 | - |
dc.identifier.bibliographicCitation | ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE, Vol.26(1) : 91, 2021-09 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.