Cited 4 times in
The differential effects of anemia on mortality in young and elderly end-stage renal disease patients
DC Field | Value | Language |
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dc.contributor.author | 강신욱 | - |
dc.contributor.author | 변석호 | - |
dc.date.accessioned | 2021-09-29T02:34:08Z | - |
dc.date.available | 2021-09-29T02:34:08Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 2211-9132 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184995 | - |
dc.description.abstract | Background: The aim of this study was to compare the effect of anemia on clinical outcomes according to age in patients with end-stage renal disease (ESRD). Methods: A total of 3,409 patients from the Clinical Research Center for ESRD were included and divided into three groups by age: age < 40 (n = 488), 40 ≤ age < 60 (n = 1,650), and age ≥ 60 (n = 1,271). We compared overall and cardiovascular mortality, and all-cause and cardiovascular hospitalization according to mean hemoglobin (Hb) concentration. Results: Among participants ≥ 60 years of age, the Hb < 10 g/dL group had greater all-cause mortality (adjusted hazard ratio [HR], 2.098; 95% confidence interval [CI], 1.567-2.808; P < 0.001) than the 10 ≤ Hb < 12 g/dL group, whereas among participants < 40 years of age, the Hb ≥ 12 g/dL group had greater mortality than the 10 ≤ Hb < 12 g/dL group. Moreover, in participants ≥ 60 years of age, the HR for all-cause hospitalization for the Hb < 10 g/dL group was significantly greater than that of the 10 ≤ Hb < 12 g/dL group (HR, 1.472; 95% CI, 1.057-2.051; P = 0.022), whereas it was significantly lower in the Hb ≥ 12 g/dL group (HR, 0.544; 95% CI, 0.362-0.820; P = 0.004) However, among participants < 40 years of age, the incidence of all-cause hospitalization did not differ according to the Hb concentration (HR, 1.273; 95% CI, 0.814-1.991; P = 0.290 for the Hb < 10 g/dL group; reference, 10 ≤ Hb < 12 g/dL; HR, 0.787; 95% CI, 0.439-1.410; P = 0.265 for Hb ≥ 12 g/dL group). Conclusion: The impact of anemia on mortality was more significant in elderly ESRD patients. Strict monitoring and management of anemia should be required for elderly ESRD patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Elsevier Korea | - |
dc.relation.isPartOf | KIDNEY RESEARCH AND CLINICAL PRACTICE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | The differential effects of anemia on mortality in young and elderly end-stage renal disease patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Eun Jeong Ko | - |
dc.contributor.googleauthor | Yong Kyun Kim | - |
dc.contributor.googleauthor | Jang-Hee Cho | - |
dc.contributor.googleauthor | Yon Su Kim | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Nam-Ho Kim | - |
dc.contributor.googleauthor | Yong-Lim Kim | - |
dc.contributor.googleauthor | Chul Woo Yang | - |
dc.contributor.googleauthor | Byung Ha Chung | - |
dc.identifier.doi | 10.23876/j.krcp.19.120 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A01849 | - |
dc.relation.journalcode | J01942 | - |
dc.identifier.eissn | 2211-9140 | - |
dc.identifier.pmid | 32457275 | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Cardiovascular diseases | - |
dc.subject.keyword | Dialysis | - |
dc.subject.keyword | Hemoglobin target | - |
dc.subject.keyword | Mortality | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | 강신욱 | - |
dc.contributor.affiliatedAuthor | 변석호 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 192 | - |
dc.citation.endPage | 201 | - |
dc.identifier.bibliographicCitation | KIDNEY RESEARCH AND CLINICAL PRACTICE, Vol.39(2) : 192-201, 2020-06 | - |
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