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De Novo Cancer Incidence after Kidney Transplantation in South Korea from 2002 to 2017

DC Field Value Language
dc.contributor.author김보연-
dc.contributor.author김윤정-
dc.contributor.author박용정-
dc.contributor.author이경아-
dc.contributor.author김윤정-
dc.contributor.author박용정-
dc.contributor.author이경아-
dc.contributor.author이정준-
dc.date.accessioned2021-09-29T02:09:07Z-
dc.date.available2021-09-29T02:09:07Z-
dc.date.issued2021-08-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/184738-
dc.description.abstractAdvances in patient care and immunosuppressive drugs have improved graft survival, resulting in an increase in kidney transplantation (KT); however, persistent immunosuppression is thought to cause late occurrence of cancer. This population-based study consisted of a total of 14,842 patients whose data from the years 2002 to 2017 were collected from the National Health Information Database in South Korea. Malignancies occurred in 7.6% of the total KT patients. Prostate and thyroid cancers were the most common in males and females, respectively. From the age-adjusted incidence analysis, Kaposi’s sarcoma showed the highest standardized incidence ratio in both male and female patients. According to the linear regression model, cancer incidence in KT recipients under immunosuppressive conditions increased by approximately 0.1% each month. Patients’ age over 39 and the use of prednisolone as an initial steroid regimen were associated with increased risk of cancer development after KT. Our regression and proportional hazards models will help clinicians to predict the approximate cancer incidence risk when monitoring KT recipients. Based on the largest available national database, screening or monitoring methods for cancer detection and prevention can be established for KT patients by considering the factors involved in cancer development.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleDe Novo Cancer Incidence after Kidney Transplantation in South Korea from 2002 to 2017-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.googleauthorBoyeon Kim-
dc.contributor.googleauthorMinjin Kang-
dc.contributor.googleauthorYoonjung Kim-
dc.contributor.googleauthorHyung Soon Lee-
dc.contributor.googleauthorBanseok Kim-
dc.contributor.googleauthorJung Jun Lee-
dc.contributor.googleauthorYongjung Park-
dc.contributor.googleauthorKyung-A Lee-
dc.identifier.doi10.3390/jcm10163530-
dc.contributor.localIdA06055-
dc.contributor.localIdA00793-
dc.contributor.localIdA01582-
dc.contributor.localIdA02647-
dc.contributor.localIdA00793-
dc.contributor.localIdA01582-
dc.contributor.localIdA02647-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.subject.keywordkidney transplantation-
dc.subject.keywordmalignancy-
dc.subject.keywordcancer risk-
dc.subject.keywordpopulation-based study-
dc.contributor.alternativeNameKim, Boyeon-
dc.contributor.affiliatedAuthor김보연-
dc.contributor.affiliatedAuthor김윤정-
dc.contributor.affiliatedAuthor박용정-
dc.contributor.affiliatedAuthor이경아-
dc.contributor.affiliatedAuthor김윤정-
dc.contributor.affiliatedAuthor박용정-
dc.contributor.affiliatedAuthor이경아-
dc.citation.volume10-
dc.citation.number16-
dc.citation.startPage3530-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.10(16) : 3530, 2021-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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