Cited 38 times in
The Metabolic Score for Insulin Resistance (METS-IR) as a Predictor of Incident Ischemic Heart Disease: A Longitudinal Study among Korean without Diabetes
DC Field | Value | Language |
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dc.contributor.author | 박병진 | - |
dc.contributor.author | 윤지현 | - |
dc.contributor.author | 이용제 | - |
dc.contributor.author | 정동혁 | - |
dc.date.accessioned | 2021-09-29T02:02:02Z | - |
dc.date.available | 2021-09-29T02:02:02Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184676 | - |
dc.description.abstract | The metabolic score for insulin resistance (METS-IR) is a novel noninsulin-based marker for assessing the risk of insulin resistance and cardiometabolic risk. However, whether METS-IR is associated with incident ischemic heart disease (IHD) risk is not well known. Therefore, we aimed to investigate the longitudinal effect of METS-IR on incident IHD risk in a large cohort of Korean adults without diabetes. Data were assessed from 17,943 participants without diabetes from the Health Risk Assessment Study (HERAS) and Korea Health Insurance Review and Assessment (HIRA) data. The participants were divided into four groups according to METS-IR index quartiles: (ln ((2 × fasting plasma glucose) + triglyceride) × body mass index)/(ln (HDL-cholesterol)). We prospectively assessed hazard ratios (HRs) with 95% confidence intervals (CIs) for IHD using multivariate Cox proportional hazard regression models over a 50-month period. During the follow-up period, 332 participants (1.9%) developed IHD. HRs of IHD for METS-IR quartiles 1–4 were 1.00, were 1.62 (95% CI 1.04–2.53), 1.87 (95% CI 1.20–2.91), and 2.11 (95% CI 1.35–3.30), respectively, after adjusting for potential confounding variables. A higher METS-IR precedes future IHD among Koreans without diabetes. Moreover, compared with metabolic syndrome, METS-IR had a better predictive value for IHD. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | JOURNAL OF PERSONALIZED MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | The Metabolic Score for Insulin Resistance (METS-IR) as a Predictor of Incident Ischemic Heart Disease: A Longitudinal Study among Korean without Diabetes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Jihyun Yoon | - |
dc.contributor.googleauthor | Donghyuk Jung | - |
dc.contributor.googleauthor | Yongjae Lee | - |
dc.contributor.googleauthor | Byoungjin Park | - |
dc.identifier.doi | 10.3390/jpm11080742 | - |
dc.contributor.localId | A01477 | - |
dc.contributor.localId | A06126 | - |
dc.contributor.localId | A02982 | - |
dc.contributor.localId | A03595 | - |
dc.relation.journalcode | J04078 | - |
dc.identifier.eissn | 2075-4426 | - |
dc.subject.keyword | metabolic score for insulin resistance | - |
dc.subject.keyword | cardiometabolic risk | - |
dc.subject.keyword | longitudinal study | - |
dc.subject.keyword | ischemic heart disease | - |
dc.contributor.alternativeName | Park, Byoung Jin | - |
dc.contributor.affiliatedAuthor | 박병진 | - |
dc.contributor.affiliatedAuthor | 윤지현 | - |
dc.contributor.affiliatedAuthor | 이용제 | - |
dc.contributor.affiliatedAuthor | 정동혁 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 742 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERSONALIZED MEDICINE, Vol.11(8) : 742, 2021-07 | - |
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