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Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma

Authors
 Sung Won Lee  ;  Jonggi Choi  ;  Seung Up Kim  ;  Young-Suk Lim 
Citation
 CLINICAL AND MOLECULAR HEPATOLOGY, Vol.27(3) : 402-412, 2021-07 
Journal Title
CLINICAL AND MOLECULAR HEPATOLOGY
ISSN
 2287-2728 
Issue Date
2021-07
Keywords
Carcinoma, Hepatocellular ; Efficacy ; Entecavir ; Hepatitis B ; Outcome ; Tenofovir
Abstract
Over the past several decades, entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have remained the first-line antiviral agents in several international guidelines. These two antiviral agents have shown similar short to intermediateterm efficacy, including virologic, biochemical, serologic, and histologic responses. However, huge controversies regarding the antiviral efficacy of ETV and TDF in preventing the development of hepatocellular carcinoma (HCC) still exist. In this review, we summarized recent studies that compared the treatment efficacy of ETV and TDF in terms of HCC development.
Files in This Item:
T202102895.pdf Download
DOI
10.3350/cmh.2021.0179
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Up(김승업) ORCID logo https://orcid.org/0000-0002-9658-8050
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184344
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