A Case of Lymphocyte-Rich Hepatocellular Carcinoma in a Patient Who Was Treated for Colon Cancer
Authors
Jae Won Song ; Ho Soo Chun ; Jae Seung Lee ; Hye Won Lee ; Beom Kyung Kim ; Seung Up Kim ; Jun Yong Park ; Sang Hoon Ahn ; Young Nyun Park ; Dai Hoon Han ; Do Young Kim
Citation
Journal of Liver Cancer (대한간암학회지), Vol.21(1) : 69-75, 2021-03
Hepatocellular carcinoma (HCC) primarily originates in the liver with hepatic differentiation. However, HCCs are not homogenous, and approximately 35% of HCC cases are classified as histopathological variants that present distinct pathologic characteristics. In particular, the lymphocyte-rich variant is the rarest subtype accounting for less than 1% of HCCs, which is not well known to date about molecular features and pathophysiology. Herein, we present a case of a patient who was suspected of metastatic liver cancer and confirmed as lymphocyte-rich HCC pathologically. A 78-year-old woman who underwent a right hemicolectomy for colon cancer was referred to our hospital for a newly detected liver mass. We could not make a decision because of insufficient evidence for diagnosis from imaging studies. After resection, we found that it was a lymphocyte-rich HCC. The pathologic features and prognostic trends of this subtype are also discussed.