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Role of agmatine in the application of neural progenitor cell in central nervous system diseases: therapeutic potentials and effects

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dc.contributor.author김종열-
dc.contributor.author이종은-
dc.contributor.author이종은-
dc.date.accessioned2021-09-29T01:14:43Z-
dc.date.available2021-09-29T01:14:43Z-
dc.date.issued2021-06-
dc.identifier.issn2093-3665-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/184265-
dc.description.abstractAgmatine, the primary decarboxylation product of L-arginine, generated from arginine decarboxylase. Since the discovery of agmatine in the mammalian brain in the 1990s, an increasing number of agmatine-mediated effects have been discovered, demonstrating the benefits of agmatine on ischemic strokes, traumatic brain injury and numerous psychological disorders such as depression, anxiety, and stress. Agmatine also has cellular protective effects and contributes to cell proliferation and differentiation in the central nervous system (CNS). Neural progenitor cells are an important component in the recovery and repair of many neurological disorders due to their ability to differentiate into functional adult neurons. Recent data has revealed that agmatine can regulate and increase proliferation and the fate of progenitor cells in the adult hippocampus. This review aims to summarise and discuss the role of agmatine in the CNS; specifically, the effects and relationship between agmatine and neural progenitor cells and how these ideas can be applied to potential therapeutic application.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Association of Anatomists-
dc.relation.isPartOfAnatomy and Cell Biology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleRole of agmatine in the application of neural progenitor cell in central nervous system diseases: therapeutic potentials and effects-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anatomy (해부학교실)-
dc.contributor.googleauthorRenée Kosonen-
dc.contributor.googleauthorSumit Barua-
dc.contributor.googleauthorJong Youl Kim-
dc.contributor.googleauthorJong Eun Lee-
dc.identifier.doi10.5115/acb.21.089-
dc.contributor.localIdA00923-
dc.contributor.localIdA03146-
dc.contributor.localIdA03146-
dc.relation.journalcodeJ00142-
dc.identifier.eissn2093-3673-
dc.identifier.pmid34162764-
dc.subject.keywordAgmatine-
dc.subject.keywordArginine-
dc.subject.keywordNeural progenitor stem cells-
dc.subject.keywordNeuroprotection-
dc.subject.keywordTherapeutic uses-
dc.contributor.alternativeNameKim, Jong Youl-
dc.contributor.affiliatedAuthor김종열-
dc.contributor.affiliatedAuthor이종은-
dc.contributor.affiliatedAuthor이종은-
dc.citation.volume54-
dc.citation.number2-
dc.citation.startPage143-
dc.citation.endPage151-
dc.identifier.bibliographicCitationAnatomy and Cell Biology, Vol.54(2) : 143-151, 2021-06-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anatomy (해부학교실) > 1. Journal Papers

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