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크기가 작은 췌장 신경내분비종양의 관리

Other Titles
 Management of Small Pancreatic Neuroendocrine Neoplasm 
Authors
 백우현  ;  이경주  ;  장성일  ;  조재희 
Citation
 Journal of Digestive Cancer Reports, Vol.9(1) : 19-24, 2021-06 
Journal Title
Journal of Digestive Cancer Reports
ISSN
 2288-1581 
Issue Date
2021-06
Keywords
Pancreatic neuroendocrine neoplasm ; Smal ; lAsymptomatic ; Non-functional
Abstract
The incidence of small and asymptomatic pancreatic neuroendocrine neoplasms (PNENs) has been increased due to the widespread use of high-resolution imaging techniques and endoscopic procedures in screening programmes. Most of PNENs are indolent neoplasms with slow-growing. However, sometimes, PNENs show local invasion or metastasis with poor prognosis. The management of small, nonfunctioning PNENs remain under debate. The National Comprehensive Cancer Network guidelines recommend observation in selected cases of small PNENs less than 2 cm. Pancreatic surgeons are divided into two factions: “the hawks,” who indicate the high risk of malignancy even in small PNENs and, therefore, the need for an aggressive surgical treatment, and the “the doves,” who accepts the risk of malignancy in some ≤ 2 cm PNENs, advocate that the risk of overtreating many benign ≤ 2 cm PNENs would be much higher. As the pancreatic surgery remains a high-risk operation with a 28–30% morbidity and 1% mortality, the decision for small PNENs is challenging.
Files in This Item:
T202102149.pdf Download
DOI
10.52927/jdcr.2021.9.1.19
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Jang, Sung Ill(장성일) ORCID logo https://orcid.org/0000-0003-4937-6167
Cho, Jae Hee(조재희) ORCID logo https://orcid.org/0000-0003-4174-0091
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184101
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