31 105

Cited 0 times in

Causes, Risk Factors, and Clinical Outcomes of Stroke in Korean Young Adults: Systemic Lupus Erythematosus is Associated with Unfavorable Outcomes

 Hyuk Sung Kwon  ;  Young Seo Kim  ;  Jong Min Lee  ;  Seong Ho Koh  ;  Hyun Young Kim  ;  Chulho Kim  ;  Seung Hoon Lee  ;  Keun Hwa Jung  ;  Young Dae Kim  ;  Hyung Min Kwon  ;  Beom Joon Kim  ;  Jeong Min Kim  ;  Bum Joon Kim  ;  Sung Hyuk Heo  ;  Dae Il Chang 
 JOURNAL OF CLINICAL NEUROLOGY, Vol.16(4) : 605-611, 2020-10 
Journal Title
Issue Date
ischemic stroke ; outcome ; systemic lupus erythematosus ; young adults
Background and purpose: The incidence of ischemic stroke (IS) in young adults is increasing, and the associated large socioeconomic impact makes understanding IS in young adults important. We investigated the causes of and risk factors for IS in young adults, and their impact on outcomes.

Methods: The Stroke in Korean Young Adults (SKY) study is a standardized multicenter prospective study involving eight medical centers of the Republic of Korea. First-ever IS patients aged 18 years to 44 years were prospectively included in this study within 7 days of stroke onset. Their outcomes at 3 months were analyzed.

Results: This study enrolled 270 patients from April 2014 to December 2018, most (67.8%) of whom were male. About 41.5% of the patients had one or more vascular risk factors from among hypertension, diabetes mellitus, and dyslipidemia. However, only half of them had received regular treatment. Arterial dissection was more common in males, and systemic lupus erythematosus (SLE) and Moyamoya disease were more common in females. The outcome was favorable (modified Rankin Scale score of 0 or 1) in 81.9% of the patients at 3 months after stroke onset. More severe initial symptoms, higher initial glucose level, and SLE as a comorbidity were associated with unfavorable outcomes.

Conclusions: Young adult IS patients in Korea exhibit low awareness and poor management of their risk factors. Although the short-term outcome was relatively favorable in those patients, having SLE was associated with unfavorable outcomes. More attention needs to be paid for improving awareness and controlling risk factors in this population.
Files in This Item:
T202007245.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Dae(김영대) ORCID logo https://orcid.org/0000-0001-5750-2616
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.