Gardnerella vaginalis에 의한 균혈증 2예

Abstract

Background :Gardnerella vaginalis, frequently isolated from the famale genital tract, in conjunction with anaerobic bacteria, is implicated as a cause of bacterial vaginosis or nonspecific vaginitis. It has also been associated with maternal and neonatal septicemia.A 34-year-old woman who was in the 13th week of pregnancy and who had a flu-like illness presented to Severance Hospital. She was febrile with leukocytosis and neutrophilia. Blood were taken for culture, and G. vaginalis was isolated from one of three specimens. The patient was treated with ampicillin and improved, A female neonate with body weight of 1,120 g was delivered vaginally after a 26 week gestation. The neonate was hypotonic and intermittently apneic. She was intubated and given artificial respiration. Blood cultures were taken, as she was a premature baby with a serum bilirubin value of 9.7 mg/dL, although she was afebrile and there was no leukocytosis or neutrophilia. G. vaginalis was isolated from two specimens. The patient was treated with ampicillin and improved. In vitro antimicrobial susceptibility testing showed that the isolates were susceptible to ampicillin, cephalothin and cefotaxime but resistant to amikacin, gentamicin and cotrimoxazole. Methods :Gardnerella vaginalis, frequently isolated from the famale genital tract, in conjunction with anaerobic bacteria, is implicated as a cause of bacterial vaginosis or nonspecific vaginitis. It has also been associated with maternal and neonatal septicemia.A 34-year-old woman who was in the 13th week of pregnancy and who had a flu-like illness presented to Severance Hospital. She was febrile with leukocytosis and neutrophilia. Blood were taken for culture, and G. vaginalis was isolated from one of three specimens. The patient was treated with ampicillin and improved, A female neonate with body weight of 1,120 g was delivered vaginally after a 26 week gestation. The neonate was hypotonic and intermittently apneic. She was intubated and given artificial respiration. Blood cultures were taken, as she was a premature baby with a serum bilirubin value of 9.7 mg/dL, although she was afebrile and there was no leukocytosis or neutrophilia. G. vaginalis was isolated from two specimens. The patient was treated with ampicillin and improved. In vitro antimicrobial susceptibility testing showed that the isolates were susceptible to ampicillin, cephalothin and cefotaxime but resistant to amikacin, gentamicin and cotrimoxazole. Results :Gardnerella vaginalis, frequently isolated from the famale genital tract, in conjunction with anaerobic bacteria, is implicated as a cause of bacterial vaginosis or nonspecific vaginitis. It has also been associated with maternal and neonatal septicemia.A 34-year-old woman who was in the 13th week of pregnancy and who had a flu-like illness presented to Severance Hospital. She was febrile with leukocytosis and neutrophilia. Blood were taken for culture, and G. vaginalis was isolated from one of three specimens. The patient was treated with ampicillin and improved, A female neonate with body weight of 1,120 g was delivered vaginally after a 26 week gestation. The neonate was hypotonic and intermittently apneic. She was intubated and given artificial respiration. Blood cultures were taken, as she was a premature baby with a serum bilirubin value of 9.7 mg/dL, although she was afebrile and there was no leukocytosis or neutrophilia. G. vaginalis was isolated from two specimens. The patient was treated with ampicillin and improved. In vitro antimicrobial susceptibility testing showed that the isolates were susceptible to ampicillin, cephalothin and cefotaxime but resistant to amikacin, gentamicin and cotrimoxazole. Conclusion :Gardnerella vaginalis, frequently isolated from the famale genital tract, in conjunction with anaerobic bacteria, is implicated as a cause of bacterial vaginosis or nonspecific vaginitis. It has also been associated with maternal and neonatal septicemia.A 34-year-old woman who was in the 13th week of pregnancy and who had a flu-like illness presented to Severance Hospital. She was febrile with leukocytosis and neutrophilia. Blood were taken for culture, and G. vaginalis was isolated from one of three specimens. The patient was treated with ampicillin and improved, A female neonate with body weight of 1,120 g was delivered vaginally after a 26 week gestation. The neonate was hypotonic and intermittently apneic. She was intubated and given artificial respiration. Blood cultures were taken, as she was a premature baby with a serum bilirubin value of 9.7 mg/dL, although she was afebrile and there was no leukocytosis or neutrophilia. G. vaginalis was isolated from two specimens. The patient was treated with ampicillin and improved. In vitro antimicrobial susceptibility testing showed that the isolates were susceptible to ampicillin, cephalothin and cefotaxime but resistant to amikacin, gentamicin and cotrimoxazole.