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Influence of antifungal pre-treatment in preparing test mycelium on MIC values of several antifungal agents against Aspergillus niger
DC Field | Value | Language |
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dc.contributor.author | 박종철 | - |
dc.date.accessioned | 2021-09-28T08:34:40Z | - |
dc.date.available | 2021-09-28T08:34:40Z | - |
dc.date.issued | 1996-07 | - |
dc.identifier.issn | 1340-3540 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183724 | - |
dc.description.abstract | Antifungal activity of two imidazoles (miconazole and ketoconazole) and one polyene (amphotericin B) was evaluated using an automatic growth analysis system. Spores ofAspergillus niger were inoculated on the polylysine-coated glass bottom of a culture vessel. A colony formed in liquid medium was exposed to an antifungal agent and subsequently washed. Based on the dynamic growth rate of a test hypha selected from the colony in response to the antifungal agent, the minimum inhibitory concentration (MIC) was evaluated. The influence of time of reading (1, 2 and 3 h after washing) on the MIC determined was investigated. MICs for test hyphae subjected to antifungal pre-treatment were compared with those for hyphae without pre-treatment. Hyphae pre-treated with an antifungal agent for 1 h were found to become adapted and tolerant to that antifungal agent. Hyphae exposed and adapted to an imidazole obtained tolerance to amphotericin B as well as to the other imidazole. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mycological Society of Japan | - |
dc.relation.isPartOf | MYCOSCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Influence of antifungal pre-treatment in preparing test mycelium on MIC values of several antifungal agents against Aspergillus niger | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학교실) | - |
dc.contributor.googleauthor | Jong-Chul Park | - |
dc.contributor.googleauthor | Kosuke Takatori | - |
dc.contributor.googleauthor | Hun-Jun Lee | - |
dc.contributor.googleauthor | Hideaki Matsuoka | - |
dc.contributor.googleauthor | Hiroshi Kurata | - |
dc.contributor.localId | A01662 | - |
dc.relation.journalcode | J04041 | - |
dc.identifier.eissn | 1618-2545 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1340354096710276 | - |
dc.contributor.alternativeName | Park, Jong Chul | - |
dc.contributor.affiliatedAuthor | 박종철 | - |
dc.citation.volume | 37 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 117 | - |
dc.citation.endPage | 120 | - |
dc.identifier.bibliographicCitation | MYCOSCIENCE, Vol.37(2) : 117-120, 1996-07 | - |
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