폐와 위장의 전이성 석회화를 동반한 부갑상선 선종 1예

Abstract

Metastatic calcification of soft tissues due to hypercalcemia is a well-recognized complication of various malignancies and renal failure. It results from metabolic derangement in which calcium salts are deposited in otherwise normal tissuel. The calcific process principally affects lungs, stomach, kidneys and other soft tissues. With advance of nuclear imaging modalities, metastatic calcification can be detected earlier so that appropriate therapy may be instituted. A case of parathyroid adenoma with metastatic pulmonary and gastric calcification is presented. She showed intense concentrations of bone-seeking radionuclide( 99mTechnetiurn) in both lungs and stomach on routine bone scan. Renal function of the patient was moderately impaired, Right inferior parathyroidectomy was performed. Her serum calcium concentration decreased postoperatively and had to be maintained with orally administered calcium and aldactazide. After the operation the clinical course has been uneventful. Follow-up bone scan performed lo days following the operation revealed persistence of lung uptake despite restoration of normal blood calcium concentration, but disappearance of gastric uptake. So we report the case of parathyroid adenoma complicating metastatic pulmonary and gastric calcification with review of literature.