Peripheral neuroepithelioma that presumed to be neural crest origin is a small round cell malignancy arising outside the central and sympathetic nervous systems. Peripheral neuroepithelioma is a rare soft-tissue neoplasm and has been confused histologically with a variety of other small cell tumors and sometimes immunohistochemical, ultrastructural and cytogenetic studies are needed for the definite diagnosis. The following case report concerns a peripheral neuroepithelioma of right foot in a 18 year-old male having difficulties in the diagnosis and showing very aggressive clinical course.