혈소판 항원

Abstract

Background: There has been rapid increase in demand for fresh frozen plasma and its derivatives in Korea. It may be due to active therapy by the clinicians especially hematologic and coagulopathy areas. So, now, the plasma is lack of supply of full demand. So, We studied the concurrent collection procedure of plasma during a plateletpheresis for the purpose of plasma supply. Methods: Over three month period from January 1996 to March 1996, we introduced a program of concurrent collection of plasma (CCP) during plateletpheresis at Korea University Guro Hospital, in which the additional plasma are collected for preparation of FFP Donors were enrolled in our 62 volunteer plateletpheresis. The 31 volunteers (group Ⅰ) were done plateletphersis only, another volunteers (group Ⅱ) were done CCP. We compared the platelet concentrate volume, to the characteristics of donor's condition and the adverse reaction during plateletpheresis between between two groups. Results: Before the plateletpheresis, there were no differences in the age, weight, height, pre-platelet count between the two groups. Also there were no adverse reactions through the procedure, such as per unit did not show significant differences between two groups. In group Ⅰ. The mean platelet concentrate volume was 300 mL, yield was 4.5×10E11 and group Ⅱ. the volume was 315 mL, the yield was 5.1×10E11 and the fresh plasma volume was 223 mL. Conclusion: We have experienced the concurrent collection procedure of plasma during a plateletpheresis from 31 volunteers without main adverse reactions.