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소아 외래 환자 마취를 위한 Ketamine 경구 전투약

Other Titles
 Oral Ketamine Premedication for Pediatric Outpatient Anesthesia 
 이기영  ;  신양식  ;  이춘수  ;  박기용  ;  이동철  ;  김종래  ;  한석주  ;  황의호 
 Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.30(1) : 58-67, 1996-01 
Journal Title
Journal of Korean Society of Anesthesiologist(대한마취과학회지)
Issue Date
Premedication, oral ; ketamine ; Anesthesia pediatric outpatient
Background: In children, fear of venipuncture and seperation from parents may produce stormy induction of anesthesia. Premedication administered by nontraumatic methods helps to decrease anxiety and minimize psychological trauma.
Methods: To define a dose of oral ketamine that would facilitate smooth induction of anesthesia for pediatric outpatient surgery without causing significant side effects, sixty children(ASA Physical Status 1; aged 1-7 years) undergoing inguinal herniorrhaphy were assigned randomly to four separate groups that received 5 mg/kg, 7 mg/kg, 10 mg/kg, or no ketamine(control group) mixed in 0.2 ml/kg cola. They were evaluated preoperatively and postoperatively for acceptance of oral ketamine, reaction to separation from their parents, acceptance of facial mask for inhalation induction, emergence delirium and postanesthetic complications.
Results: The 7 mg/kg and 10 mg/kg doses were well accepted; provided predictable sedation within 22-25 minutes; allowed calm seperation from parents and good induction conditions. However, the 10 mg/kg dose prolonged discharge time from recovery room, probably due to delayed recovery. Emergence deliriums were observed in two of all ketamine administered children(4.4%). And the incidences of postanesthetic complications such as vomiting, decreased appetite, lethargy, nausea, nightmare, behavioral change were slightly higher in ketamine administered groups, compared to the control group.
Conclusion: The authors conclude that an oral dose of 7 mg/kg ketamine is well accepted in young children undergoing outpatient surgery for inguinal hernia and provides relatively predictable and satisfactory sedation without prolongation of discharge time and significant side effects.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Ki Young(이기영) ORCID logo https://orcid.org/0000-0003-4893-3195
Han, Seok Joo(한석주) ORCID logo https://orcid.org/0000-0001-5224-1437
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