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Oral-Gut Microbiome Axis in Gastrointestinal Disease and Cancer
DC Field | Value | Language |
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dc.contributor.author | 박광균 | - |
dc.contributor.author | 송나영 | - |
dc.contributor.author | 임미화 | - |
dc.contributor.author | 정원윤 | - |
dc.date.accessioned | 2021-05-26T16:59:57Z | - |
dc.date.available | 2021-05-26T16:59:57Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182940 | - |
dc.description.abstract | It is well-known that microbiota dysbiosis is closely associated with numerous diseases in the human body. The oral cavity and gut are the two largest microbial habitats, playing a major role in microbiome-associated diseases. Even though the oral cavity and gut are continuous regions connected through the gastrointestinal tract, the oral and gut microbiome profiles are well-segregated due to the oral-gut barrier. However, the oral microbiota can translocate to the intestinal mucosa in conditions of the oral-gut barrier dysfunction. Inversely, the gut-to-oral microbial transmission occurs as well in inter- and intrapersonal manners. Recently, it has been reported that oral and gut microbiomes interdependently regulate physiological functions and pathological processes. Oral-to-gut and gut-to-oral microbial transmissions can shape and/or reshape the microbial ecosystem in both habitats, eventually modulating pathogenesis of disease. However, the oral-gut microbial interaction in pathogenesis has been underappreciated to date. Here, we will highlight the oral-gut microbiome crosstalk and its implications in the pathogenesis of the gastrointestinal disease and cancer. Better understanding the role of the oral-gut microbiome axis in pathogenesis will be advantageous for precise diagnosis/prognosis and effective treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | CANCERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Oral-Gut Microbiome Axis in Gastrointestinal Disease and Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학교실) | - |
dc.contributor.googleauthor | Se-Young Park | - |
dc.contributor.googleauthor | Byeong-Oh Hwang | - |
dc.contributor.googleauthor | Mihwa Lim | - |
dc.contributor.googleauthor | Seung-Ho Ok | - |
dc.contributor.googleauthor | Sun-Kyoung Lee | - |
dc.contributor.googleauthor | Kyung-Soo Chun | - |
dc.contributor.googleauthor | Kwang-Kyun Park | - |
dc.contributor.googleauthor | Yinling Hu | - |
dc.contributor.googleauthor | Won-Yoon Chung | - |
dc.contributor.googleauthor | Na-Young Song | - |
dc.identifier.doi | 10.3390/cancers13092124 | - |
dc.contributor.localId | A01429 | - |
dc.contributor.localId | A05713 | - |
dc.contributor.localId | A03362 | - |
dc.contributor.localId | A03676 | - |
dc.relation.journalcode | J03449 | - |
dc.identifier.eissn | 2072-6694 | - |
dc.identifier.pmid | 33924899 | - |
dc.subject.keyword | GI cancer | - |
dc.subject.keyword | GI disease | - |
dc.subject.keyword | gut microbiome | - |
dc.subject.keyword | oral microbiome | - |
dc.subject.keyword | oral–gut microbiome axis | - |
dc.contributor.alternativeName | Park, Kwang Kyun | - |
dc.contributor.affiliatedAuthor | 박광균 | - |
dc.contributor.affiliatedAuthor | 송나영 | - |
dc.contributor.affiliatedAuthor | 임미화 | - |
dc.contributor.affiliatedAuthor | 정원윤 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2124 | - |
dc.identifier.bibliographicCitation | CANCERS, Vol.13(9) : 2124, 2021-04 | - |
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