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Pediatric characteristics and the dose of propofol for sedation during radiological examinations: a retrospective analysis

Authors
 Ji Young Min  ;  Jeong-Rim Lee  ;  Yhen Seoung Kang  ;  Jung Hwan Ho  ;  Hyo Jin Byon 
Citation
 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, Vol.49(2) : 300060521990992, 2021-02 
Journal Title
 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 
ISSN
 0300-0605 
Issue Date
2021-02
Keywords
Sedation ; age ; body surface area ; children ; imaging ; pediatric ; propofol
Abstract
Objective: The present study aimed to investigate patients' characteristics that can affect the dose of propofol required to sedate children undergoing imaging. Methods: In this retrospective, observational study, we reviewed medical records of children aged 0 to 18 years who were classified as having American Society of Anesthesiologists status 1 or 2 and they underwent imaging under propofol sedation between January 2011 and August 2016. Collected data included patients' demographics, propofol doses, duration of sedation, and complications. Regression analysis was performed to determine patients' characteristics that may affect the dose of propofol required to induce sedation. Results: A total of 925 patients were included. Simple linear regression showed that the dose of propofol was correlated with age, height, weight, and body surface area. Using the results of multiple linear regression, the following formula was used to estimate the dose of propofol (mg) for sedation: 0.75 + 0.14 × age (months) + 45.82 × body surface area (m2). Conclusion: A child's age, height, and body surface area should be considered when deciding the induction dose of propofol. Additionally, the formula that we have proposed can be used to estimate the dose of propofol required to induce sedation in children undergoing imaging.
Files in This Item:
T202100901.pdf Download
DOI
10.1177/0300060521990992
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Byon, Hyo Jin(변효진)
Lee, Jeong Rim(이정림) ORCID logo https://orcid.org/0000-0002-7425-0462
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182287
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