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Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis

Authors
 Jun Chen  ;  Xixi Zhang  ;  Reid Millican  ;  Jennifer Sherwood  ;  Sean Martin  ;  Hanjoong Jo  ;  Young-Sup Yoon  ;  Brigitta C Brott  ;  Ho-Wook Jun 
Citation
 ADVANCED DRUG DELIVERY REVIEWS, Vol.170 : 142-199, 2021-03 
Journal Title
 ADVANCED DRUG DELIVERY REVIEWS 
ISSN
 0169-409X 
Issue Date
2021-03
Keywords
Atherosclerosis ; Clinical use ; Imaging contrast agents ; Nanomaterials ; Theranostic agents ; Therapeutic delivery system
Abstract
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries, leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is the leading cause of mortality in the United States. Researchers have strived to design nanomaterials of various functions, ranging from non-invasive imaging contrast agents, targeted therapeutic delivery systems to multifunctional nanoagents able to target, diagnose, and treat atherosclerosis. Therefore, this review aims to summarize recent progress (2017-now) in the development of nanomaterials and their applications to improve atherosclerosis diagnosis and therapy during the preclinical and clinical stages of the disease.
Full Text
https://www.sciencedirect.com/science/article/pii/S0169409X21000053
DOI
10.1016/j.addr.2021.01.005
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
Yonsei Authors
Yoon, Young Sup(윤영섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182049
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