10 12

Cited 0 times in

Physiologic and hemodynamic changes in patients undergoing open abdominal cytoreductive surgery with hyperthermic intraperitoneal chemotherapy

Authors
 Myoung Hwa Kim  ;  Young Chul Yoo  ;  Sun Joon Bai  ;  Kang-Young Lee  ;  Nayeon Kim  ;  Ki Young Lee 
Citation
 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, Vol.49(1) : 300060520983263, 2021-01 
Journal Title
 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 
ISSN
 0300-0605 
Issue Date
2021-01
Keywords
Anesthesia ; hemodynamic monitoring ; hyperthermic intraperitoneal chemotherapy ; open abdominal cytoreductive surgery ; physiologic change ; transpulmonary thermodilution measurement
Abstract
Objective: We aimed to determine the physiological and hemodynamic changes in patients who were undergoing hyperthermic intraperitoneal chemotherapy (HIPEC) cytoreductive surgeries. Methods: This prospective, observational study enrolled 21 patients who were undergoing elective cytoreductive surgery with HIPEC at our hospital over 2 years. We collected vital signs, hemodynamic parameters including global end-diastolic volume index (GEVI) and extravascular lung water index (ELWI) using the VolumeView™ system, and arterial blood gas analysis from all patients. Data were recorded before skin incision (T1); 30 minutes before HIPEC initiation (T2); 30 (T3), 60 (T4), and 90 (T5) minutes after HIPEC initiation; 30 minutes after HIPEC completion (T6); and 10 minutes before surgery completion (T7). Results: Patients showed an increase in body temperature and cardiac index and a decrease in the systemic vascular resistance index. GEDI was 715.4 (T1) to 809.7 (T6), and ELWI was 6.9 (T1) to 7.3 (T5). Conclusions: HIPEC increased patients' body temperature and cardiac output and decreased systemic vascular resistance. Although parameters that were extracted from the VolumeView™ system were within their normal ranges, transpulmonary thermodilution approach is helpful in intraoperative hemodynamic management during open abdominal cytoreductive surgery with HIPEC.Trial registry name: ClinicalTrials.govTrial registration number: NCT02325648URL: https://clinicaltrials.gov/ct2/results?cond=NCT02325648&term.
Files in This Item:
T202100262.pdf Download
DOI
10.1177/0300060520983263
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myoung Hwa(김명화) ORCID logo https://orcid.org/0000-0003-4723-9425
Bai, Sun Joon(배선준) ORCID logo https://orcid.org/0000-0001-5027-3232
Yoo, Young Chul(유영철) ORCID logo https://orcid.org/0000-0002-6334-7541
Lee, Kang Young(이강영)
Lee, Ki Young(이기영) ORCID logo https://orcid.org/0000-0003-4893-3195
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/182035
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links