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Prognostic value of neutrophil/lymphocyte ratio and mean platelet volume/platelet ratio for 1-year mortality in critically ill patients

 Ham, Sung Yeon  ;  Yoon, Hei Jin  ;  Nam, Sang Beom  ;  Yun, Byung Hwan  ;  Eum, Darhae  ;  Shin, Cheung Soo 
 SCIENTIFIC REPORTS, Vol.10(1) : 21513, 2020-12 
Journal Title
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Several studies have reported that the neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) are associated with poor prognosis. This study investigated whether NLR and/or the MPV/platelet ratio could function as predictive markers of mortality in critically ill patients. We retrospectively reviewed 1,154 patients admitted to the intensive care unit (ICU) between January 2017 and December 2017. Patients were divided into 2 groups according to 1-year mortality. We compared the NLR and MPV/platelet ratio on each day of ICU admission. Patients were classified into tertiles based on their NLR and MPV/platelet ratios, and the incidence of 1-year mortality was compared. Kaplan-Meier survival curves were plotted to evaluate their potential as prognostic factors for 1-year mortality. The NLR and MPV/platelet ratio were higher in the non-survivor group than in the survivor group. The incidence of 1-year mortality was the highest in the third tertile for both the NLR and MPV/platelet ratio. The MPV/platelet ratio was an independent predictor for 1-year mortality based on the Kaplan-Meier survival analysis. Our data showed that the MPV/platelet ratio is a predictive factor for 1-year mortality in critically ill patients.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Nam, Sang Beom(남상범) ORCID logo https://orcid.org/0000-0002-9704-1866
Shin, Cheung Soo(신증수) ORCID logo https://orcid.org/0000-0001-7829-8458
Yoon, Hei Jin(윤혜진)
Eum, Dahae(음다혜) ORCID logo https://orcid.org/0000-0003-0048-1476
Ham, Sung Yeon(함성연) ORCID logo https://orcid.org/0000-0001-8619-4595
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