Cited 4 times in
Borderline-High Mean Corpuscular Volume Levels Are Associated with Arterial Stiffness among the Apparently Healthy Korean Individuals
DC Field | Value | Language |
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dc.contributor.author | 박병진 | - |
dc.date.accessioned | 2021-01-19T08:16:47Z | - |
dc.date.available | 2021-01-19T08:16:47Z | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 2005-6443 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/181545 | - |
dc.description.abstract | Background: High mean corpuscular volume (MCV) has been implicated in various health problems, such as anemia, liver disease, and thyroid disease. However, the clinical significance of borderline-high MCV is poorly understood in the primary care setting. This study aimed to investigate whether borderline-high MCV was related to arterial stiffness in Korean adults as measured by brachial-ankle pulse wave velocity (baPWV). Methods: This cross-sectional study comprised 582 participants aged >30 years who underwent routine health examinations. Borderline-high MCV was defined as over 95.0 fl (>90th percentile) after excluding participants with MCV of ≥100 fl or ≤80 fl, and high baPWV was defined as >1,600 cm/s (>90th percentile). The odds ratios (ORs) and 95% confidence intervals (CIs) for high baPWV according to borderline-high MCV were calculated using multiple logistic regression analyses after adjusting for the confounding variables. Results: The mean age of the study population was 47.8±11.7 years, and 56.9% of the participants were male. Compared to that in the control group, the OR (95% CI) of high baPWV in those with a borderline-high MCV was 3.68 (1.39-9.74) after adjusting for age, sex, body mass index, alcohol intake, smoking status, regular exercise, mean blood pressure, fasting plasma glucose, triglyceride, high-density lipoprotein cholesterol, C-reactive protein, γ-glutamyltransferase, uric acid, hypertension medication, and diabetes medication. Conclusion: Borderline-high MCV was independently associated with arterial stiffness among apparently healthy Korean individuals. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한가정의학회 | - |
dc.relation.isPartOf | Korean Journal of Family Medicine (가정의학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Borderline-High Mean Corpuscular Volume Levels Are Associated with Arterial Stiffness among the Apparently Healthy Korean Individuals | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Haneul Kwon | - |
dc.contributor.googleauthor | Byoungjin Park | - |
dc.identifier.doi | 10.4082/kjfm.19.0061 | - |
dc.contributor.localId | A01477 | - |
dc.relation.journalcode | J02007 | - |
dc.identifier.eissn | 2092-6715 | - |
dc.identifier.pmid | 31955550 | - |
dc.subject.keyword | Erythrocyte Indices | - |
dc.subject.keyword | Pulse Wave Analysis | - |
dc.subject.keyword | Vascular Stiffness | - |
dc.contributor.alternativeName | Park, Byoung Jin | - |
dc.contributor.affiliatedAuthor | 박병진 | - |
dc.citation.volume | 41 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 387 | - |
dc.citation.endPage | 391 | - |
dc.identifier.bibliographicCitation | Korean Journal of Family Medicine (가정의학회지), Vol.41(6) : 387-391, 2020-11 | - |
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