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Borderline-High Mean Corpuscular Volume Levels Are Associated with Arterial Stiffness among the Apparently Healthy Korean Individuals

DC FieldValueLanguage
dc.contributor.author박병진-
dc.date.accessioned2021-01-19T08:16:47Z-
dc.date.available2021-01-19T08:16:47Z-
dc.date.issued2020-11-
dc.identifier.issn2005-6443-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181545-
dc.description.abstractBackground: High mean corpuscular volume (MCV) has been implicated in various health problems, such as anemia, liver disease, and thyroid disease. However, the clinical significance of borderline-high MCV is poorly understood in the primary care setting. This study aimed to investigate whether borderline-high MCV was related to arterial stiffness in Korean adults as measured by brachial-ankle pulse wave velocity (baPWV). Methods: This cross-sectional study comprised 582 participants aged >30 years who underwent routine health examinations. Borderline-high MCV was defined as over 95.0 fl (>90th percentile) after excluding participants with MCV of ≥100 fl or ≤80 fl, and high baPWV was defined as >1,600 cm/s (>90th percentile). The odds ratios (ORs) and 95% confidence intervals (CIs) for high baPWV according to borderline-high MCV were calculated using multiple logistic regression analyses after adjusting for the confounding variables. Results: The mean age of the study population was 47.8±11.7 years, and 56.9% of the participants were male. Compared to that in the control group, the OR (95% CI) of high baPWV in those with a borderline-high MCV was 3.68 (1.39-9.74) after adjusting for age, sex, body mass index, alcohol intake, smoking status, regular exercise, mean blood pressure, fasting plasma glucose, triglyceride, high-density lipoprotein cholesterol, C-reactive protein, γ-glutamyltransferase, uric acid, hypertension medication, and diabetes medication. Conclusion: Borderline-high MCV was independently associated with arterial stiffness among apparently healthy Korean individuals.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한가정의학회-
dc.relation.isPartOfKorean Journal of Family Medicine (가정의학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleBorderline-High Mean Corpuscular Volume Levels Are Associated with Arterial Stiffness among the Apparently Healthy Korean Individuals-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학교실)-
dc.contributor.googleauthorHaneul Kwon-
dc.contributor.googleauthorByoungjin Park-
dc.identifier.doi10.4082/kjfm.19.0061-
dc.contributor.localIdA01477-
dc.relation.journalcodeJ02007-
dc.identifier.eissn2092-6715-
dc.identifier.pmid31955550-
dc.subject.keywordErythrocyte Indices-
dc.subject.keywordPulse Wave Analysis-
dc.subject.keywordVascular Stiffness-
dc.contributor.alternativeNamePark, Byoung Jin-
dc.contributor.affiliatedAuthor박병진-
dc.citation.volume41-
dc.citation.number6-
dc.citation.startPage387-
dc.citation.endPage391-
dc.identifier.bibliographicCitationKorean Journal of Family Medicine (가정의학회지), Vol.41(6) : 387-391, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers

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