Vitiligo is a relatively common, acquired hypopigmentary disorder caused by the loss of epidermal melanocytes.
It is characterized by asymptomatic, well-circumscribed round to oval-shaped whitish patches that vary in size.
Depending on various clinical features, vitiligo is classified into several types, that is, non-segmental, segmental,
and undetermined/unclassified vitiligo. The uniform classification of vitiligo is very important in predicting its clinical
course and prognosis and communication among researchers. In particular, segmental vitiligo is a highly distinctive
subtype of vitiligo considering its clinical features and prognosis. It usually has an onset early in life and spreads
rapidly within the affected area limited to one segment of the integument. Signs of vitiligo activity such as Koebnerʼs
phenomenon, trichrome vitiligo, inflammatory vitiligo, and confetti-like lesions give useful information to start
treatments to block the progression of the disease. Lastly, other hypopigmentary disorders should be distinguished
from vitiligo to make the correct diagnosis and prescribe the right treatment. In this report, I review the clinical
features of vitiligo, various subtypes according to classification, and the importance for differential diagnosis of
hypopigmentary disorders from vitiligo.