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Outcome of Extracorporeal Ventricular Assist Device for Cardiogenic Shock as a Bridge to Transplantation

Authors
 Hyo-Hyun Kim  ;  Jung-Hoon Shin  ;  Jung-Hwan Kim  ;  Young-Nam Youn 
Citation
 Korean Journal of Thoracic and Cardiovascular Surgery, Vol.53(6) : 368-374, 2020-12 
Journal Title
 Korean Journal of Thoracic and Cardiovascular Surgery 
ISSN
 2233-601X 
Issue Date
2020-12
Keywords
Heart failure ; Heart transplantation ; Heart-assist devices
Abstract
Background: The extracorporeal ventricular assist device (e-VAD) system is designed for left ventricular support using a permanent life support console. This study aimed to determine the impact of temporary e-VAD implantation bridging on posttransplant outcomes. Methods: We reviewed the clinical records of 6 patients with the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) profile 1, awaiting heart transplantation, who were provided with temporary e-VAD from 2018 to 2019. The circuit comprised a single centrifugal pump without an oxygenator. The e-VAD inflow cannula was inserted into the apex of the left ventricle, and the outflow cannula was positioned in the ascending aorta. The median follow-up duration was 8.4±6.9 months. Results: After e-VAD implantation, lactate dehydrogenase levels significantly decreased, and Sequential Organ Failure Assessment scores significantly improved. Bedside rehabilitation was possible in 5 patients. After a mean e-VAD support duration of 14.5±17.3 days, all patients were successfully bridged to transplantation. After transplantation, 5 patients survived for at least 6 months. Conclusion: e-VAD may reverse end-organ dysfunction and improve outcomes in INTERMACS I heart transplant patients.
Files in This Item:
T202005442.pdf Download
DOI
10.5090/kjtcs.20.023
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jung Hwan(김정환)
Kim, Hyohyun(김효현) ORCID logo https://orcid.org/0000-0002-1608-9674
Youn, Young Nam(윤영남)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/181326
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