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Application of Multiparameter Diffusion Weighted Imaging of In Vitro Scanning Pleural Effusion in Different Diseases
DC Field | Value | Language |
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dc.contributor.author | 양홍뢰 | - |
dc.date.accessioned | 2020-12-22T05:52:00Z | - |
dc.date.available | 2020-12-22T05:52:00Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180968 | - |
dc.description.abstract | A preliminary study to evaluate the sequential alterations of the apparent diffusion coefficients (ADC) values of pleural effusions using in vitro magnetic resonance diffusion-weighted imaging. Fifteen pleural effusions (3 chronic renal insufficiency, 4 infection, 4 malignancy, 4 trauma) were included in this prospective study. Single-shot echo-planar spin-echo DWI using 3 Tesla MRI was performed with three b factors (500, 1000, and 2000 s/mm²) and the ADC values of aspirated pleural fluids were measured immediately, 2 and 4 weeks at the ADC map. The initial ADCs of the traumatic effusions were significantly lower than the others (1.62±1.2510-3mm²/s vs 1.94±0.0510-3mm²/s). When measured 28 days later, the ADC of the effusions origin from chronic renal insufficiency showed an increasing pattern, but those of pneumonia and malignant effusions showed a decreasing pattern. The ADC values with b factor of 2000s/mm² are more comparable than the others because signal intensities of pleural fluids were more homogeneous. Conclusions: ADC values may differentiate the character of different types of pleural effusion and both of the b factor and time factor affected the identification of pleural effusion. 체외 확산 가중 MR 영상촬영을 사용하여 흉막삼출물의 외관확산계수(ADC) 값의 순차적 변화를 평가하기 위함이다. 흉막삼출 15 개 샘플(만성신부전 3 개, 감염 4 개, 악성 4 개, 외상 4 개)을 대상으로 하였다. 3 테슬라 자기공명영상을 이용한 싱글샷 에코-플래너 스핀 에코 DWI 는 3개의 b 인자(500, 1000, 2000s/mm²)를 사용하여 시행되었고 흉수 ADC 값은 1, 2, 4 주 후 ADCs 맵에서 측정되였다. 외상 흉막삼출의 ADC는 다른 흉막삼출보다 매우 낮았다(1.62±1.25x10-3mm²/s vs. 1.94±0.05x10-3mm²/s). 28 일 후에 측정했을 때 만성 신부전증에서 비롯된 흉막삼출의 ADC 는 증가하는 패턴을 보였지만, 폐렴과 악성 흉막삼출은 감소하는 패턴을 보였다. B인자 2000s/mm² 의 ADC 값이 다른 b인자의 ADC 값과는 통계적으로 유의한 차이를 보였다. ADC 값은 여러 유형의 흉막삼출의 특성을 평가할 수 있고 B인자와 시간인자는 흉막삼출의 식별에 영향을 줄 수 있다. | - |
dc.description.statementOfResponsibility | open | - |
dc.publisher | Graduate School, Yonsei University | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Application of Multiparameter Diffusion Weighted Imaging of In Vitro Scanning Pleural Effusion in Different Diseases | - |
dc.title.alternative | 다중 파라미터 확산강조영상에서 각종의 질병 흉막삼출의 체외 스캔 | - |
dc.type | Thesis | - |
dc.contributor.college | Graduate School, Yonsei University | - |
dc.contributor.department | Dept. of Medicine | - |
dc.description.degree | 석사 | - |
dc.contributor.alternativeName | YANG,HONGLEI | - |
dc.type.local | Thesis | - |
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