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Inverse association between triglyceride glucose index and muscle mass in Korean adults: 2008-2011 KNHANES

DC FieldValueLanguage
dc.contributor.author이준혁-
dc.contributor.author이지원-
dc.date.accessioned2020-12-11T08:03:18Z-
dc.date.available2020-12-11T08:03:18Z-
dc.date.issued2020-11-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180755-
dc.description.abstractBackground: Since sarcopenia is an important risk factor for falls or cardiovascular disease, early detection and prevention of sarcopenia are being increasingly emphasized. Emerging evidence has indicated relationships between sarcopenia, insulin resistance, and inflammation. The triglyceride glucose (TyG) index, a novel surrogate marker of insulin resistance and systemic inflammation, has not yet been shown to be associated with sarcopenia. This study aimed to examine the relationship between the TyG index and muscle mass in Korean adults. Methods: This study included 15,741 non-diabetic adults over 19 years old using data from the 2008-2011 Korea National Health and Nutrition Examination Survey. Participants were divided into three groups according to tertiles of the TyG index. A low skeletal muscle mass index (LSMI) was defined by the Foundation for the National Institutes of Health Sarcopenia Project criteria. A weighted multivariate logistic regression model was used to analyze relationships between TyG index tertiles and LSMI. Results: The ORs (95% CIs) for LSMI in the second and third TyG tertiles, compared to the first tertile, were 1.463 (1.131-1.892) and 1.816 (1.394-2.366), respectively, after adjusting for confounding factors. Higher TyG index values were also associated with increased odds of LSMI in adults under 65 years who did not exercise regularly, who consumed less than 30 g of alcohol per day, who did not currently smoke, and who ate less than 1.5 g of protein/kg/day. Conclusion: The TyG index was significantly and positively associated with LSMI in Korean adults.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfLIPIDS IN HEALTH AND DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleInverse association between triglyceride glucose index and muscle mass in Korean adults: 2008-2011 KNHANES-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학교실)-
dc.contributor.googleauthorSung-Ho Ahn-
dc.contributor.googleauthorJun-Hyuk Lee-
dc.contributor.googleauthorJi-Won Lee-
dc.identifier.doi10.1186/s12944-020-01414-4-
dc.contributor.localIdA05837-
dc.contributor.localIdA03203-
dc.contributor.localIdA03203-
dc.relation.journalcodeJ02169-
dc.identifier.eissn1476-511X-
dc.identifier.pmid33222694-
dc.subject.keywordChronic inflammation-
dc.subject.keywordInflammatory cytokines-
dc.subject.keywordInsulin resistance-
dc.subject.keywordLow skeletal muscle index-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordPublic health-
dc.subject.keywordSarcopenia-
dc.subject.keywordTriglyceride and glucose index-
dc.contributor.alternativeNameLee, Jun-Hyuk-
dc.contributor.affiliatedAuthor이준혁-
dc.contributor.affiliatedAuthor이지원-
dc.contributor.affiliatedAuthor이지원-
dc.citation.volume19-
dc.citation.number1-
dc.citation.startPage243-
dc.identifier.bibliographicCitationLIPIDS IN HEALTH AND DISEASE, Vol.19(1) : 243, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers

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