Cited 8 times in
Age as a risk factor for steroid-induced ocular hypertension in the non-paediatric population
DC Field | Value | Language |
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dc.contributor.author | 김민 | - |
dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 배형원 | - |
dc.contributor.author | 성공제 | - |
dc.contributor.author | 최웅락 | - |
dc.contributor.author | 최은영 | - |
dc.date.accessioned | 2020-12-01T18:06:54Z | - |
dc.date.available | 2020-12-01T18:06:54Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0007-1161 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180609 | - |
dc.description.abstract | Background/aims: To evaluate the age-related risk of steroid-induced ocular hypertension by analysing intraocular pressure (IOP) changes after intravitreal dexamethasone (DEX, Ozurdex) implant injection. Methods: A retrospective observational study was conducted among patients (n=455; 570 eyes) who had received DEX injection. IOP was measured prior to injection and after 1 week and 1, 2, 3, 6 and 12 months. Results were divided into seven categories based on patient age: 16-30, 31-40, 41-50, 51-60, 61-70, 71-80 and 81-90 years. The IOP elevation rate was compared among the groups. Results: The IOP elevation rate was 42.9% in patients aged ≤30 years (35.3%, 28.3%, 14.9%, 12.2%, 8.4% and 9.1% in the 31-40, 41-50, 51-60, 61-70, 71-80 and 81-90 groups, respectively). Regardless of how IOP was measured, there was an increasing trend in the incidence of IOP elevation with decreasing age. Furthermore, there was a significant stepwise increase in the OR with decreasing age groups. After the 51-60 group was set as the reference point, the ORs (95% CIs) were 5.048 (1.436 to 17.747), 3.671 (1.101 to 12.238), 2.538 (1.043 to 6.178), 0.947 (0.431 to 2.078), 0.713 (0.312 to 1.626) and 0.646 (0.137 to 3.048) in the ≤30, 31-40, 41-50, 61-70, 71-80 and 81-90 groups, respectively. Conclusion: The rate of adverse elevations in IOP after steroid use was significantly lower in older patients than in younger patients. Therefore, caution is required when prescribing steroids to younger patients (<51 years). | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | BMJ Pub. Group | - |
dc.relation.isPartOf | BRITISH JOURNAL OF OPHTHALMOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Age as a risk factor for steroid-induced ocular hypertension in the non-paediatric population | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Wungrak Choi | - |
dc.contributor.googleauthor | Hyoung Won Bae | - |
dc.contributor.googleauthor | Eun Young Choi | - |
dc.contributor.googleauthor | Minha Kim | - |
dc.contributor.googleauthor | Eun Woo Kim | - |
dc.contributor.googleauthor | Chan Yun Kim | - |
dc.contributor.googleauthor | Min Kim | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.identifier.doi | 10.1136/bjophthalmol-2019-314559 | - |
dc.contributor.localId | A00455 | - |
dc.contributor.localId | A01035 | - |
dc.contributor.localId | A01814 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A04123 | - |
dc.contributor.localId | A05056 | - |
dc.relation.journalcode | J00412 | - |
dc.identifier.eissn | 1468-2079 | - |
dc.identifier.pmid | 32071035 | - |
dc.identifier.url | https://bjo.bmj.com/content/104/10/1423.long | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | glaucoma | - |
dc.subject.keyword | intraocular pressure | - |
dc.subject.keyword | retina | - |
dc.contributor.alternativeName | Kim, Min | - |
dc.contributor.affiliatedAuthor | 김민 | - |
dc.contributor.affiliatedAuthor | 김찬윤 | - |
dc.contributor.affiliatedAuthor | 배형원 | - |
dc.contributor.affiliatedAuthor | 성공제 | - |
dc.contributor.affiliatedAuthor | 최웅락 | - |
dc.contributor.affiliatedAuthor | 최은영 | - |
dc.citation.volume | 104 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1423 | - |
dc.citation.endPage | 1429 | - |
dc.identifier.bibliographicCitation | BRITISH JOURNAL OF OPHTHALMOLOGY, Vol.104(10) : 1423-1429, 2020-10 | - |
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