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Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement

 Grace Lai-Hung Wong  ;  Vincent Wai-Sun Wong  ;  Alex Thompson  ;  Jidong Jia  ;  Jinlin Hou  ;  Cosmas Rinaldi Adithya Lesmana  ;  Adityo Susilo  ;  Yasuhito Tanaka  ;  Wah-Kheong Chan  ;  Ed Gane  ;  Arlinking K Ong-Go  ;  Seng-Gee Lim  ;  Sang Hoon Ahn  ;  Ming-Lung Yu  ;  Teerha Piratvisuth  ;  Henry Lik-Yuen Chan 
 LANCET GASTROENTEROLOGY & HEPATOLOGY, Vol.5(8) : 776-787, 2020-08 
Journal Title
Issue Date
Antiviral Agents / adverse effects ; Antiviral Agents / therapeutic use ; Betacoronavirus ; Coronavirus Infections / complications ; Coronavirus Infections / drug therapy ; Coronavirus Infections / epidemiology* ; Humans ; Liver Diseases / etiology ; Liver Diseases / therapy* ; Pandemics* ; Pneumonia, Viral / complications ; Pneumonia, Viral / drug therapy ; Pneumonia, Viral / epidemiology* ; Risk Factors
The COVID-19 pandemic has spread rapidly worldwide. It is common to encounter patients with COVID-19 with abnormal liver function, either in the form of hepatitis, cholestasis, or both. The clinical implications of liver derangement might be variable in different clinical scenarios. With growing evidence of its clinical significance, it would be clinically helpful to provide practice recommendations for various common clinical scenarios of liver derangement during the COVID-19 pandemic. The Asia-Pacific Working Group for Liver Derangement during the COVID-19 Pandemic was formed to systematically review the literature with special focus on the clinical management of patients who have been or who are at risk of developing liver derangement during this pandemic. Clinical scenarios covering the use of pharmacological treatment for COVID-19 in the case of liver derangement, and assessment and management of patients with chronic hepatitis B or hepatitis C, non-alcoholic fatty liver disease, liver cirrhosis, and liver transplantation during the pandemic are discussed.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
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