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Non-invasive postoperative monitoring of pedicled rat skin flap using laser speckle contrast imaging

Authors
 Jinhyuck Im  ;  Tae Hoon Kong  ;  Jin Sil Choi  ;  Young Joon Seo  ;  Eun Chang Choi  ;  Byungjo Jung  ;  Ji-Hoon Kim 
Citation
 MICROVASCULAR RESEARCH, Vol.132 : :104050, 2020-11 
Journal Title
 MICROVASCULAR RESEARCH 
ISSN
 0026-2862 
Issue Date
2020-11
Keywords
Laser speckle contrast imaging ; Pedicled flap ; Postoperative monitoring
Abstract
Purpose: This study used non-invasive laser speckle contrast imaging (LSCI) modality to evaluate the blood flow changes in murine flap model and to investigate the clinical feasibility of the LSCI for postoperative monitoring. Methods: Ten of 6-8 weeks old Spraque-Dawley rats with superficial inferior epigastric vessel based pedicled skin flaps were used in this experiment. The color changes of skin flap were evaluated by naked eyes and the LSCI modality 6, 24, and 48 h after surgery. Results: In vessel ligated region of skin flap, skin color began to change to a bluish color immediately postoperatively. At 24 h postoperatively, skin necrosis was detectable with the naked eye and total necrosis occurred at 48 h postoperatively. Changes in laser speckle signal were consistent with changes observed with the naked eye, and blood flow index also presented significant differences between the ligated and non-ligated region. Conclusion: These correlated laser speckle signal patterns suggest that non-invasive monitoring of perfusion by LSCI is a useful technology that may be used to identify the ischemic skin flap.
Full Text
https://www.sciencedirect.com/science/article/pii/S0026286220301102
DOI
10.1016/j.mvr.2020.104050
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Eun Chang(최은창)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/180241
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