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Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature

Authors
 Moonsik Kim  ;  Haerim Chung  ;  Woo Ick Yang  ;  Hyeon Joo Jeong 
Citation
 JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, Vol.54(5) : 426-431, 2020-09 
Journal Title
 JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE 
ISSN
 2383-7837 
Issue Date
2020-09
Keywords
Intravascular large B cell lymphoma ; Kidney glomerulus ; Peritubular capillary
Abstract
Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up.
Files in This Item:
T202003592.pdf Download
DOI
10.4132/jptm.2020.06.18
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Moonsik(김문식) ORCID logo https://orcid.org/0000-0002-5804-8790
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Chung, Hae Rim(정해림) ORCID logo https://orcid.org/0000-0002-7926-9285
Jeong, Hyeon Joo(정현주) ORCID logo https://orcid.org/0000-0002-9695-1227
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/180004
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