Image analysis of the intracranial lead bending phenomenon during deep brain stimulation

Abstract

Background: An accurate and precise surgical procedure is crucial for patient safety and treatment efficacy of deep brain stimulation (DBS).

Objectives: To investigate the characteristics of intracranial lead bending phenomenon after DBS, and to suggest the methods to avoid bending-related complications.

Methods: A retrospective review of brain computed tomography scans after DBS was performed. Using 3-dimensional reconstruction, the maximal distance between the planned trajectory and actual lead location was measured. When the distance exceeded the lead body diameter, the lead was considered bent. The distance between the bending point and planned trajectory, and the relative direction between the bending point and lead securing site were analyzed. Changes over time in the range of lead bending and depth were analyzed when possible.

Results: A total of 190 implanted leads in 102 patients were analyzed; 104 leads (54.7%) were bent. The average deviation of bent leads was 2.3 mm (range, 1.3-7.1 mm). Thirty-five (18.4%) and seven leads (3.7%) had deviations exceeding twice and three times the lead body diameter, respectively. Angles between the deviation point and securing site at the skull ranged from 135-180° in 83 leads (53.2%), 45-135° in 58 (37.2%), and 0-45° in 15 (9.6%). Among 17 leads that were initially bent, 16 had less deviation compared to baseline. The lead depth increased in 35 (92.1%) of 38 leads by 1.2 mm (range, 0.1-4.7 mm).

Conclusion: The extent of lead bending should be considered during the planning and procedural phases of intracranial lead implantation for DBS.