Increasing Malaria Parasite Clearance Time after Chloroquine Therapy, South Korea, 2000-2016
Authors
Seong Yeon Park ; Yoon Soo Park ; Yoonseon Park ; Yee Gyung Kwak ; Je Eun Song ; Kkot Sil Lee ; Shin-Hyeong Cho ; Sang-Eun Lee ; Hyun-Il Shin ; Joon-Sup Yeom
Chloroquine ; Plasmodium vivax ; South Korea ; fever clearance time ; hydroxychloroquine ; malaria ; parasite clearance time ; parasites ; primaquine ; retrospective studies
Abstract
We reviewed the clinical efficacy of chloroquine for Plasmodium vivax malaria, the changing trend of parasite clearance time, and fever clearance time during 2000-2016 in South Korea. Median parasite clearance time and fever clearance time increased significantly over the study period. Chloroquine was mostly underdosed when used to treat P. vivax malaria.