59 141

Cited 0 times in

Normal Reference Values for Left Atrial Strain and Its Determinants from a Large Korean Multicenter Registry

 Byung Joo Sun  ;  Jae Hyeong Park  ;  Minyeong Lee  ;  Jin Oh Choi  ;  Ju Hee Lee  ;  Mi Seung Shin  ;  Mi Jeong Kim  ;  Hae Ok Jung  ;  Jeong Rang Park  ;  Il Suk Sohn  ;  Hyungseop Kim  ;  Hyung Kwan Kim  ;  Goo Yeong Cho  ;  Jin Sun Park  ;  Chi Young Shim  ;  Sung Hee Shin  ;  Kye Hun Kim  ;  Woo Shik Kim  ;  Seung Woo Park 
 Journal of Cardiovascular Imaging, Vol.28(3) : 186-198, 2020-07 
Journal Title
Journal of Cardiovascular Imaging
Issue Date
LA function ; LA strain ; Speckle-tracking echocardiography
Background: Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for LA strain remain elusive. We aimed to present LA strain with reservoir, conduit, and contractile components and associated parameters in a large-sized group of healthy individuals.

Methods: The present study was from a prospective multicenter registry in South Korea. Subjects who had no history of cardiovascular disease with adequate images were eligible for inclusion. LA reservoir, conduit, and contractile strains (LASRES, LASCD and LASCT, respectively) were measured. Left ventricular global longitudinal strain (LV GLS) and early and late diastolic strain rates (DSRe and DSRa, respectively) were also evaluated.

Results: Among a total of 324 subjects (mean age: 49 ± 16 years, 167 females), the mean LASRES, LASCD, and LASCT values were 35.9% ± 10.6%, 21.9% ± 9.3%, and 13.9% ± 3.6%, respectively. Mean LV GLS was -20.4% ± 2.2%, and mean DSRe and DSRa were 1.6 ± 0.4 s-1 and 0.8 ± 0.3 s-1, respectively. With aging, LASRES and LASCD showed significant decreases. Factors showing independent associations with LASRES were age (B = -0.425, p < 0.001), DSRe (B = 4.706, p = 0.001), and LV GLS (B = -1.081, p < 0.001). Age (B = -0.319, p < 0.001), DSRe (B = 4.140, p = 0.002), DSRa (B = -3.409, p = 0.018), and LV GLS (B = -0.783, p < 0.001) showed associations with LASCD. With LASCT, only DSRa showed a correlation (R = 0.277, p < 0.001).

Conclusions: We presented LA strain in a large-sized group of healthy subjects. Age is a significant determinant of LA function. Associations of LA strain with diastolic strain rates and LV GLS reflect cardiac mechanics.
Files in This Item:
T202002401.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Shim, Chi Young(심지영) ORCID logo https://orcid.org/0000-0002-6136-0136
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.