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Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view

 Andreas Kronbichler  ;  Maria Effenberger  ;  Michael Eisenhut  ;  Keum Hwa Lee  ;  Jae Il Shin 
 AUTOIMMUNITY REVIEWS, Vol.19(7) : 102570, 2020-07 
Journal Title
Issue Date
Anti-Bacterial Agents / therapeutic use ; Betacoronavirus ; Coronavirus Infections / immunology ; Coronavirus Infections / mortality* ; Coronavirus Infections / therapy* ; Cytokine Release Syndrome / virology ; Humans ; Hydroxychloroquine / therapeutic use ; Lung / physiopathology ; Morbidity ; Mouthwashes ; Nasal Sprays ; Pandemics ; Plant Preparations / therapeutic use ; Pneumonia, Viral / immunology ; Pneumonia, Viral / mortality* ; Pneumonia, Viral / therapy* ; Povidone-Iodine / therapeutic use ; Sambucus / chemistry ; Smoking Cessation ; Steroids / therapeutic use
COVID-19 ; Cytokine storm ; Early treatment ; Mortality
Now COVID-19 is causing a severe public health emergency and the mortality is rapidly increasing all over the world. In the current pandemic era, although there have been many efforts to diagnose a number of patients with symptoms or close contacts, there is no definite guideline for the initial therapeutic approach for them and therefore, many patients have been dying due to a hyperinflammatory immunological reaction labeled as "cytokine storm". Severe patients are hospitalized and the treatment is done, though they have not been established yet. Currently, however, no treatment is provided for those who are isolated at home or shelter until they get severe symptoms, which will increase the harms to the patients. In this review, we discuss some important points dedicated to the management of patients with COVID-19, which should help reducing morbidity and mortality. In this era, we suggest 7 recommendations to rescue the patients and to reduce the morbidity and mortality due to COVID-19 based on the immunological point of view.
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1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
Lee, Keum Hwa(이금화) ORCID logo https://orcid.org/0000-0002-1511-9587
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